CAS 17162-39-9

Phenylephrine tartrate

Description:

Phenylephrine tartrate is a pharmaceutical compound primarily used as a decongestant and a mydriatic agent. It is the tartrate salt of phenylephrine, which is an alpha-1 adrenergic agonist. This compound is characterized by its ability to constrict blood vessels, leading to reduced nasal congestion and increased blood pressure. In its pure form, phenylephrine tartrate appears as a white to off-white crystalline powder, which is soluble in water and has a slightly bitter taste. The molecular structure includes a phenolic group, contributing to its pharmacological activity. It is commonly administered in various formulations, including oral tablets and injectable solutions. The compound is generally well-tolerated, though it may cause side effects such as hypertension, reflex bradycardia, or local irritation at the site of administration. Due to its vasoconstrictive properties, phenylephrine tartrate is often utilized in clinical settings for managing hypotension during anesthesia and for treating nasal congestion associated with colds or allergies.

Formula: C₁₃H₁₉NO₈

InChI: InChI=1/C9H13NO2.C4H6O6/c1-10-6-9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-5,9-12H,6H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2+/m0./s1

InChI key: InChIKey=NHKOTKKHHYKARN-NDAAPVSOSA-N

SMILES: [C@@H]([C@H](C(O)=O)O)(C(O)=O)O.[C@@H](CNC)(O)C1=CC(O)=CC=C1

Synonyms:

• 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol 2,3-dihydroxybutanedioate (salt)
• <span class="text-smallcaps">L</span>-Phenylephedrine bitartrate
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (R)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:1) (salt)
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (αR)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1)
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (αR)-, (2R,3R)-2,3-dihydroxybutanedioate (1:1) (salt)
• Benzyl alcohol, m-hydroxy-α-[(methylamino)methyl]-, (-)-, tartrate (1:1) (salt)
• Phenylephrine bitartrate
• Phenylephrine tartrate
• Phenylephrine hydrogentartrate
• L-Phenylephedrine bitartrate
• (R)-(beta-,3-dihydroxyphenethyl)methylammonium hydrogen [R-(R*,R*)]-tartrate
• BENZENEMETHANOL, 3-HYDROXY-ALPHA-[(METHYLAMINO)METHYL]-, (AR)-, (2R,3R)-2,3-DIHYDROXYBUTANEDIOATE (1:1) (SALT)
• (-)-PHENYLEPHRINE-(+)-HYDROGEN TARTRATE
• (R)-[2-Hydroxy-2-(3-hydroxyphenyl)-ethyl)methylammonium-hydrogen-[R-(R*,R*)]-tartrate
• BENZENEMETHANOL,3-HYDROXY-A-[(METHYLAMINO)METHYL]-,(AR)-,(2R,3R)-2,3-DIHYDROXYBUTANEDIOATE

Phenylephrine Bitartrate

CAS: 17162-39-9

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₉H₁₃NO₂·C₄H₆O₆

Color and Shape: White Off-White Powder

Molecular weight: 167.09463

Ref: 45-1532950

(-)-Phenylephrine hydrogentartrate

CAS: 17162-39-9

(-)Phenylephrine is a medication that belongs to the group of drugs called sympathomimetics. This drug is a potent vasoconstrictor that causes blood vessels to narrow and increases blood pressure. (-)Phenylephrine is used in humans as a pharmaceutical dosage for treatment of chronic bronchitis, hay fever, and other allergic reactions. It also has been shown to inhibit guanylate cyclase activity and can be used for the treatment of asthma. (-)Phenylephrine inhibits the action of two enzymes: cyclase and phosphodiesterase. This inhibition leads to an increased level of cAMP, which binds with G protein-coupled receptors in tissues that are rich in smooth muscle cells such as the airways or urinary bladder. The binding of cAMP with these receptors causes an increase in intracellular calcium ion levels, leading to relaxation of smooth muscles and improved breathing or urination.

Formula: C₉H₁₃NO₂·C₄H₆O₆

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 317.29 g/mol

Ref: 3D-FP33906