CAS 17181-21-4

Estra-1,3,5(10)-triene-3,16,17-triol, tris(hydrogen sulfate), (16alpha ,17beta)-

Description:

Estra-1,3,5(10)-triene-3,16,17-triol, tris(hydrogen sulfate), (16alpha,17beta)-, commonly referred to in the context of steroid chemistry, is a complex organic compound characterized by its steroidal structure, which includes multiple hydroxyl groups and sulfate moieties. This compound is derived from estradiol and features a triene system, indicating the presence of three conjugated double bonds within its steroid backbone. The presence of hydroxyl groups contributes to its hydrophilicity, while the sulfate groups enhance its solubility in aqueous environments, making it relevant in biological systems. The stereochemistry, denoted by the (16alpha,17beta) configuration, indicates specific spatial arrangements of atoms that can influence the compound's biological activity and interaction with receptors. This compound is often studied for its potential roles in hormonal regulation and therapeutic applications, particularly in the context of reproductive health and endocrine function. Its CAS number, 17181-21-4, serves as a unique identifier for regulatory and research purposes.

Formula: C₁₈H₂₄O₁₂S₃

InChI: InChI=1/C18H24O12S3/c1-18-7-6-13-12-5-3-11(28-31(19,20)21)8-10(12)2-4-14(13)15(18)9-16(29-32(22,23)24)17(18)30-33(25,26)27/h3,5,8,13-17H,2,4,6-7,9H2,1H3,(H,19,20,21)(H,22,23,24)(H,25,26,27)/t13-,14-,15+,16-,17+,18+/m1/s1

Synonyms:

• Estriol-3,16,17-trisulfate
• (16Alpha,17Beta)-Estra-1,3,5(10)-Triene-3,16,17-Triyl Tris(Hydrogen Sulfate)
• Estra-1,3,5(10)-triene-3,16,17-triol, tris(hydrogen sulfate), (16alpha,17beta)-

Estriol trisulfate-ammonium salt

CAS: 17181-21-4

Estriol trisulfate-ammonium salt is a potent anticancer agent that has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound is derived from urine and acts as an inhibitor of kinases, which are proteins involved in the regulation of cell growth and division. Estriol trisulfate-ammonium salt is an analog of quetiapine, a drug used to treat schizophrenia and bipolar disorder. It has been found to be effective against various types of cancer in Chinese hamster ovary cells and human tumor cell lines. The compound works by inhibiting the activity of specific kinases involved in cancer cell proliferation, making it a promising candidate for targeted cancer therapy.

Formula: C₁₈H₂₄O₁₂S₃

Purity: Min. 95%

Molecular weight: 528.6 g/mol

Ref: 3D-SAA18121