CAS 17238-47-0

1-Naphthyl Glucosiduronic Acid

Description:

1-Naphthyl Glucosiduronic Acid is a chemical compound characterized by its structure, which consists of a naphthalene ring linked to a glucuronic acid moiety. This compound is typically used in biochemical applications, particularly in the study of enzyme activity and metabolic processes. It serves as a substrate for various glucuronidation reactions, where it can be conjugated with other substances to enhance solubility and facilitate excretion. The presence of the naphthyl group contributes to its hydrophobic characteristics, while the glucuronic acid portion provides polar functional groups that can interact with biological systems. This compound is often utilized in research settings to investigate the metabolism of drugs and xenobiotics, as well as in the development of assays for enzyme activity, particularly those involving UDP-glucuronosyltransferases. Its CAS number, 17238-47-0, allows for precise identification in chemical databases and literature. Overall, 1-Naphthyl Glucosiduronic Acid is an important tool in pharmacology and toxicology studies.

Formula: C₁₆H₁₆O₇

InChI: InChI=1/C16H16O7/c17-11-12(18)14(15(20)21)23-16(13(11)19)22-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11-14,16-19H,(H,20,21)/t11-,12-,13-,14?,16+/m0/s1

InChI key: InChIKey=KEQWBZWOGRCILF-JHZZJYKESA-N

SMILES: O(C=1C2=C(C=CC1)C=CC=C2)[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O

Synonyms:

• 1-Naphthalenyl -D-Glucopyranosiduronic Acid
• 1-Naphthalenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 1-Naphthol -D-Glucuronide
• 1-Naphthol glucuronide
• 1-Naphthol β-<span class="text-smallcaps">D</span>-glucuronide
• 1-Naphthyl glucuronide
• 1-Naphthyl β-<span class="text-smallcaps">D</span>-glucosiduronic acid
• Glucopyranosiduronic acid, 1-naphthyl, β-<span class="text-smallcaps">D</span>-
• a-Naphthol Glucuronide
• a-Naphthyl -D-Glucuronide
• a-Naphthyl -Glucuronide
• naphthalen-1-yl beta-D-glucopyranosiduronic acid
• α-Naphthyl β-<span class="text-smallcaps">D</span>-glucuronide
• α-Naphthyl β-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 1-naphthalenyl
• β-D-Glucopyranosiduronic acid, 1-naphthalenyl
• 1-Naphthalenyl β-D-glucopyranosiduronic acid
• α-Naphthyl β-D-glucuronide
• Glucopyranosiduronic acid, 1-naphthyl, β-D-
• 1-Naphthyl b-D-glucuronide
• 1-Naphthol β-D-Glucuronide
• 1-Naphthalenyl

1-Naphthol b-D-glucuronide

CAS: 17238-47-0

Ref: 7W-GC9771

1-Naphthyl β-D-glucuronide

CAS: 17238-47-0

1-Naphthyl beta-D-glucuronide (NPG) is a chromogenic enzyme substrate used to detect the presence of β-glucuronidase activity. Upon hydrolysis by the enzyme, it produces a yellow product that can be detected by spectrophotometry or visually. It is commonly used in clinical assays to detect the presence of the enzyme in urine samples, as elevated levels can indicate liver or urinary tract diseases. It is also utilized in environmental testing, as some bacteria strains can produce the enzyme as a by-product, making NPG a useful tool for detecting these strains in contaminated water or food sources.

Formula: C₁₆H₁₆O₇

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 320.29 g/mol

Ref: 3D-EN15504