CAS 17241-40-6

2-Hydroxy-3-methylanthraquinone

Description:

2-Hydroxy-3-methylanthraquinone, with the CAS number 17241-40-6, is an organic compound belonging to the anthraquinone family, characterized by its polycyclic aromatic structure. This compound features a hydroxyl group (-OH) and a methyl group (-CH3) attached to the anthraquinone framework, which contributes to its chemical reactivity and potential applications. It typically appears as a solid, often exhibiting a deep color due to its conjugated system, which can absorb light in the visible spectrum. The presence of the hydroxyl group enhances its solubility in polar solvents and can influence its reactivity, making it a candidate for various chemical reactions, including oxidation and reduction processes. 2-Hydroxy-3-methylanthraquinone is also of interest in dye manufacturing, as it can serve as a precursor or intermediate in the synthesis of dyes and pigments. Additionally, its structural features may impart biological activity, warranting investigation in fields such as medicinal chemistry. Safety data should be consulted for handling and exposure guidelines, as with all chemical substances.

Formula: C₁₅H₁₀O₃

InChI: InChI=1S/C15H10O3/c1-8-6-11-12(7-13(8)16)15(18)10-5-3-2-4-9(10)14(11)17/h2-7,16H,1H3

InChI key: InChIKey=RNJHIYAJJKOFIO-UHFFFAOYSA-N

SMILES: O=C1C=2C(C(=O)C=3C1=CC=CC3)=CC(O)=C(C)C2

Synonyms:

• 2-Hydroxy-3-methyl-9,10-anthracenedione
• 2-Hydroxy-3-methylanthraquinone
• 2-Methyl-3-hydroxyanthraquinone
• 3-Hydroxy-2-methylanthraquinone
• Anthraquinone, 2-hydroxy-3-methyl-
• Anthraquinone,2-hydroxy-3-methyl- (6CI,8CI)
• 9,10-Anthracenedione, 2-hydroxy-3-methyl-

2-Hydroxy-3-methylanthraquine

CAS: 17241-40-6

Formula: C₁₅H₁₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 238.2381

Ref: IN-DA00AKVD

2-Hydroxy-3-methylanthraquinone

CAS: 17241-40-6

2-Hydroxy-3-methylanthraquinone triggers U937 cell apoptosis via p-p38MAPK, downregulates p-ERK1/2, and activates caspase-3.

Formula: C₁₅H₁₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 238.24

Ref: TM-TN1211

2-Hydroxy-3-methylanthraquinone

CAS: 17241-40-6

Applications 2-Hydroxy-3-methylanthraquinone is a derivative of anthraquinone (A679245) which is an important precursor for many drugs, including Emodin (E523000), Aloe-emodin (A575400), Antimalarials such as Rufgallol, and also Antineoplastics used in the treatment of cancer, such as mitoxantrone (M373425), pixantrone (P552500), and the anthracyclines.
References Pan, X., et al.: Biochem. Eng. J., 5, 173 (2000), Macleod, L.C., et al.: Org. Synth., 14:4; (2005); McDonald, M., et al.: Drugs Exp. Clin. Res., 10, 745 (1984); Cavalletti, E. et al.: Invest. New Drugs, 25, 187 (2007);

Formula: C₁₅H₁₀O₃

Color and Shape: Dark Green Solid

Molecular weight: 238.24

Ref: TR-H946680