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CAS 172426-86-7

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Despropylene Gatifloxacin

Description:
Despropylene Gatifloxacin, identified by its CAS number 172426-86-7, is a synthetic fluoroquinolone antibiotic derived from gatifloxacin. It exhibits broad-spectrum antibacterial activity, primarily targeting gram-negative and some gram-positive bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication and repair. This compound is characterized by its ability to penetrate bacterial cell membranes effectively, enhancing its therapeutic efficacy. Despropylene Gatifloxacin is often studied for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, which influence its clinical application. It is typically administered in various formulations, including oral and intravenous routes, depending on the infection being treated. The compound's safety profile and potential side effects, such as gastrointestinal disturbances or central nervous system effects, are also important considerations in its use. As with other fluoroquinolones, caution is advised regarding its use in specific populations, including those with a history of tendon disorders or certain neurological conditions. Overall, Despropylene Gatifloxacin represents a significant advancement in the development of antibacterial agents.
Formula:C16H18FN3O4
InChI:InChI=1/C16H18FN3O4/c1-24-15-12(19-5-4-18)11(17)6-9-13(15)20(8-2-3-8)7-10(14(9)21)16(22)23/h6-8,19H,2-5,18H2,1H3,(H,22,23)
SMILES:COc1c(c(cc2c1n(cc(c2=O)C(=O)O)C1CC1)F)NCCN
Synonyms:
  • 7-[(2-Aminoethyl)amino]-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo- 3-quinolinecarboxylic Acid
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