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CAS 172690-48-1

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N5-Acetyl-N2-Fmoc-L-Ornithine

Description:
N5-Acetyl-N2-Fmoc-L-Ornithine, with the CAS number 172690-48-1, is a synthetic amino acid derivative that plays a significant role in peptide synthesis and bioconjugation applications. This compound features an acetyl group at the N5 position and a Fmoc (9-fluorenylmethoxycarbonyl) protecting group at the N2 position of L-ornithine, which is an amino acid that is not incorporated into proteins but is important in the urea cycle and as a precursor for polyamines. The Fmoc group is commonly used in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under acidic conditions. The acetyl modification enhances the solubility and stability of the compound. N5-Acetyl-N2-Fmoc-L-Ornithine is typically utilized in the development of peptide-based therapeutics and research, particularly in the synthesis of peptides that require specific modifications for biological activity or targeting. Its unique structure allows for versatile applications in medicinal chemistry and biochemistry.
Formula:C22H24N2O5
Synonyms:
  • (2S)-5-acetamido-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoic acid
  • 5-acetamido-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
  • N5-Acetyl-N2-Fmoc-L-Ornithine
  • L-Ornithine, N5-acetyl-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-acetamidopentanoic acid
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