CAS 172732-52-4

2-Cyanophenylboronic acid 1,3-propanediol cyclic ester

Description:

2-Cyanophenylboronic acid 1,3-propanediol cyclic ester, identified by its CAS number 172732-52-4, is a chemical compound that features a boronic acid functional group, which is known for its ability to form reversible covalent bonds with diols. This characteristic makes it particularly useful in various applications, including organic synthesis and medicinal chemistry. The presence of the cyanophenyl group contributes to its electronic properties, potentially enhancing its reactivity and interaction with biological targets. The cyclic ester structure, derived from 1,3-propanediol, suggests that the compound may exhibit unique solubility and stability characteristics. Generally, boronic acids are utilized in Suzuki coupling reactions, which are pivotal in the formation of carbon-carbon bonds, making this compound valuable in the synthesis of complex organic molecules. Additionally, the compound's properties may include moderate polarity and potential for hydrogen bonding, influencing its behavior in different solvents and environments. Overall, 2-Cyanophenylboronic acid 1,3-propanediol cyclic ester is a versatile compound with significant implications in chemical research and development.

Formula: C₁₀H₁₀BNO₂

InChI: InChI=1/C10H10BNO2/c12-8-9-4-1-2-5-10(9)11-13-6-3-7-14-11/h1-2,4-5H,3,6-7H2

SMILES: c1ccc(c(c1)C#N)B1OCCCO1

Synonyms:

• 2-(1,3,2-Dioxaborinan-2-Yl)Benzonitrile
• 2-(1,3,2-Dioxaborolan-2-Yl)Benzonitrile
• 2-Cyanophenylboronic acid 1,3-propanediol ester
• 2-Cyanophenylboronic acid-1,3-propanediol cyclic ester

Benzonitrile, 2-(1,3,2-dioxaborinan-2-yl)-

CAS: 172732-52-4

Formula: C₁₀H₁₀BNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 187.0029

Ref: IN-DA00HZL3

Perampanel Impurity 8

CAS: 172732-52-4

Formula: C₁₀H₁₀BNO₂

Color and Shape: Pale Brown Solid

Molecular weight: 187.01

Ref: 4Z-P-181010

2-Cyanobenzeneboronic acid, propane-1,3-diol ester

CAS: 172732-52-4

2-Cyanobenzeneboronic acid, propane-1,3-diol ester

Formula: C₁₀H₁₀BNO₂

Purity: ≥95%

Color and Shape: off-white solid

Molecular weight: 187.00g/mol

Ref: 54-OR7188

2-Cyanophenylboronic Acid 1,3-Propanediol Ester

CAS: 172732-52-4

Formula: C₁₀H₁₀BNO₂

Purity: >97.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 187.01

Ref: 3B-C2993

2-(2-Cyanophenyl)-1,3,2-dioxaborinane

Controlled Product

CAS: 172732-52-4

Stability Hygroscopic
Applications 2-(2-Cyanophenyl)-1,3,2-dioxaborinane is used in the synthesis of AMPA receptor antagonists in the treatment of neurological diseases causing dysfunction of glutamatergic neurotransmission. Also used in the small scale synthesis of Perampanel (P285520), an AMPA receptor antagonist.
References Hibi, S. et al.: J. Med. Chem., 55, 10584 (2012); McElhinny, C. et al.: Synthesis, 44, 57 (2012);

Formula: C₁₀H₁₀BNO₂

Color and Shape: Neat

Molecular weight: 187.0

Ref: TR-C987675

2-Cyanophenylboronic acid,1,3-propanediol

CAS: 172732-52-4

Formula: C₁₀H₁₀BNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 187.01

Ref: 10-F045270

Perampanel Impurity 8

CAS: 172732-52-4

Formula: C₁₀H₁₀BNO₂

Molecular weight: 187.01

Ref: ST-EA-CP-P219027