CAS 172733-08-3

Methyl 2-[[3-(2-amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetate

Description:

Methyl 2-[[3-(2-amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetate, identified by its CAS number 172733-08-3, is a complex organic compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This substance features a methyl ester functional group, contributing to its solubility and reactivity. The presence of an amino group indicates potential for hydrogen bonding and reactivity in biological systems, while the acetyl and ethyl substituents enhance its lipophilicity. The compound's structure suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its ability to interact with biological targets. Its specific properties, such as melting point, boiling point, and solubility, would depend on the molecular interactions and the environment in which it is studied. Overall, this compound exemplifies the complexity and diversity of organic molecules used in various chemical and biological applications.

Formula: C₂₂H₂₂N₂O₅

InChI: InChI=1S/C22H22N2O5/c1-3-15-20(21(26)22(23)27)19-16(24(15)12-14-8-5-4-6-9-14)10-7-11-17(19)29-13-18(25)28-2/h4-11H,3,12-13H2,1-2H3,(H2,23,27)

InChI key: InChIKey=VJYDOJXJUCJUHL-UHFFFAOYSA-N

SMILES: C(C(N)=O)(=O)C=1C=2C(N(CC3=CC=CC=C3)C1CC)=CC=CC2OCC(OC)=O

Synonyms:

• Acetic acid, 2-[[3-(2-amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]-, methyl ester
• LY 333013
• Acetic acid, [[3-(aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]-, methyl ester
• Varespladib methyl
• Methyl 2-[[3-(2-amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetate

Varespladib methyl

CAS: 172733-08-3

Varespladib methyl

Purity: ≥98%

Molecular weight: 394.42g/mol

Ref: 54-BUP12788

Varespladib Methyl

CAS: 172733-08-3

Formula: C₂₂H₂₂N₂O₅

Molecular weight: 394.43

Ref: 4Z-V-107003

Varespladib methyl

Controlled Product

CAS: 172733-08-3

Varespladib methyl is a secretory phospholipase A2 inhibitor that blocks the production of inflammatory lipids, such as low-density lipoprotein-cholesterol (LDL-C) and non-high-density lipoprotein cholesterol (non-HDL-C). Varespladib methyl has been shown to be effective in clinical studies for the treatment of heart disease. It also has anti-infectious effects against infectious diseases by inhibiting the production of oxygen transport proteins. Varespladib methyl is not effective in patients with type 2 diabetes, but it does have diagnostic properties for high sensitivity C reactive protein (hsCRP) levels.

Formula: C₂₂H₂₂N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 394.42 g/mol

Ref: 3D-XGA73308

Varespladib methyl

CAS: 172733-08-3

Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.

Formula: C₂₂H₂₂N₂O₅

Purity: 99.42% - 99.97%

Color and Shape: Solid

Molecular weight: 394.42

Ref: TM-T17218