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CAS 1729-17-5

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Guanidine, N,N,N′,N′-tetramethyl-, hydrochloride (1:1)

Description:
Guanidine, N,N,N′,N′-tetramethyl-, hydrochloride (1:1), commonly referred to as tetramethylguanidine hydrochloride, is a quaternary ammonium compound characterized by its strong basicity and solubility in water. It is typically encountered as a white crystalline solid. The compound features a guanidine core with four methyl groups attached to the nitrogen atoms, enhancing its nucleophilicity and making it a potent base in organic synthesis. Tetramethylguanidine hydrochloride is often utilized as a catalyst in various chemical reactions, including those involving the formation of carbon-carbon bonds and in the synthesis of heterocycles. Its ability to stabilize carbanions makes it valuable in organic chemistry. Additionally, it is used in biochemical applications, particularly in the study of enzyme mechanisms and protein interactions. Safety precautions should be observed when handling this compound, as it can be irritating to the skin and eyes. Proper storage in a cool, dry place is recommended to maintain its stability and efficacy.
Formula:C5H13N3·ClH
InChI:InChI=1S/C5H13N3.ClH/c1-7(2)5(6)8(3)4;/h6H,1-4H3;1H
InChI key:InChIKey=GMGZEOLIKDSQTL-UHFFFAOYSA-N
SMILES:C(N(C)C)(N(C)C)=N.Cl
Synonyms:
  • 1,1,3,3-Tetramethylguanidinium chloride
  • Guanidine, N,N,N′,N′-tetramethyl-, hydrochloride (1:1)
  • Guanidine, N,N,N′,N′-tetramethyl-, monohydrochloride
  • Guanidine, 1,1,3,3-tetramethyl-, monohydrochloride
  • 1,1,3,3-Tetramethylguanidine hydrochloride
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