CAS 172906-90-0

1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine

Description:

1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine, with CAS number 172906-90-0, is a chemical compound that belongs to the class of piperazine derivatives. This substance features a piperazine ring, which is a six-membered heterocyclic compound containing two nitrogen atoms. The presence of a cyclohexyl group and a naphthalene derivative contributes to its structural complexity and potential biological activity. The methoxy group on the naphthalene moiety may influence its solubility and interaction with biological targets. Compounds of this nature are often investigated for their pharmacological properties, including potential applications in neuropharmacology or as therapeutic agents. The specific characteristics, such as melting point, boiling point, solubility, and reactivity, would depend on the compound's molecular structure and functional groups. As with many organic compounds, safety data and handling precautions are essential for laboratory work involving this substance.

Formula: C₂₄H₃₈N₂O

InChI: InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3

InChI key: InChIKey=PHRCDWVPTULQMT-UHFFFAOYSA-N

SMILES: C(CCN1CCN(CC1)C2CCCCC2)C3C=4C(=C(OC)C=CC4)CCC3

Synonyms:

• PB 28
• 1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine
• Piperazine, 1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]-

PB28 dihydrochloride

CAS: 172906-90-0

Formula: C₂₄H₄₀Cl₂N₂O

Purity: ≥ 99.0%

Color and Shape: White solid

Molecular weight: 443.49

Ref: 7W-GK5739

PB28

CAS: 172906-90-0

PB28: A potent σ2 agonist (Ki 0.68 nM), σ1 antagonist (Ki 0.38 nM), with anti-tumor properties and inhibits SARS-CoV-2 interactions.

Formula: C₂₄H₃₈N₂O

Color and Shape: Solid

Molecular weight: 370.581

Ref: TM-T39176

PB 28 dihydrochloride

CAS: 172906-90-0

PB 28 is a cyclohexylpiperazine derivative and an inhibitor of the endoplasmic sigma-1 and sigma-2 receptors; it was first developed in 1996. In 2020, PB 28 has proven to be a strong anti–SARS-CoV-2 agent in vitro.

Formula: C₂₄H₄₀Cl₂N₂O

Purity: Min. 95%

Molecular weight: 443.49 g/mol

Ref: 3D-BP177452