CAS 17302-46-4

Benzoic acid, 2-hydroxy-5-nitro-, methyl ester

Description:

Benzoic acid, 2-hydroxy-5-nitro-, methyl ester, also known as methyl 2-hydroxy-5-nitrobenzoate, is an organic compound characterized by its ester functional group derived from benzoic acid. It features a nitro group and a hydroxyl group positioned on the benzene ring, which contribute to its chemical reactivity and properties. The presence of the hydroxyl group imparts some degree of polarity, while the nitro group can enhance the compound's acidity and influence its electronic properties. This compound is typically a solid at room temperature and is soluble in organic solvents. It is often used in organic synthesis and may serve as an intermediate in the production of various pharmaceuticals and agrochemicals. Additionally, due to its structural features, it may exhibit biological activity, making it of interest in medicinal chemistry. Safety data should be consulted for handling and potential hazards, as nitro compounds can be sensitive and may pose environmental risks.

Formula: C₈H₇NO₅

InChI: InChI=1S/C8H7NO5/c1-14-8(11)6-4-5(9(12)13)2-3-7(6)10/h2-4,10H,1H3

InChI key: InChIKey=UUBFELFUKFJSRD-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=CC(N(=O)=O)=CC=C1O

Synonyms:

• (2-Iodoethyl)Benzene
• 2-(Methoxycarbonyl)-4-Nitrophenolate
• 2-Hydroxy-5-nitrobenzoic acid methyl ester
• Benzoic acid, 2-hydroxy-5-nitro-, methyl ester
• Methyl 2-Hydroxy-5-Nitrobenzoate
• Methyl 5-nitro-2-hydroxybenzoate
• Salicylic acid, 5-nitro-, methyl ester
• Methyl 5-nitrosalicylate

Methyl 2-hydroxy-5-nitrobenzoate, 98%

CAS: 17302-46-4

Methyl 2-hydroxy-5-nitrobenzoate is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU

Formula: C₈H₆NO₅

Purity: 98%

Color and Shape: White to pale cream to cream to orange, Crystals or powder or crystalline powder

Molecular weight: 196.14

Ref: 02-B25278

Methyl 2-hydroxy-5-nitrobenzoate

CAS: 17302-46-4

Formula: C₈H₇NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 197.1449

Ref: IN-DA007VMP

Methyl 2-hydroxy-5-nitro-benzoate

CAS: 17302-46-4

Methyl 2-hydroxy-5-nitro-benzoate

Purity: 98%

Molecular weight: 197.14g/mol

Ref: 54-OR52922

Methyl 5-nitrosalicylate

CAS: 17302-46-4

Methyl 5-nitrosalicylate is a chemical compound that belongs to the group of 4-hydroxycoumarin derivatives. It is an inhibitor of the reaction between salicylic acid and nitrous acid, inhibiting the formation of 5-nitrosalicylic acid. Methyl 5-nitrosalicylate has shown inhibitory activity against various nitro compounds, including benzofurans. The inhibitory effect on oxidation reactions may be due to its ability to act as a ligand and form coordination complexes with metal ions such as copper, zinc, and iron. Methyl 5-nitrosalicylate also has anti-inflammatory properties that are due to its ability to inhibit prostaglandin synthesis by blocking cyclooxygenase enzyme activity.
Methyl 5-nitrosalicylate can be synthesized in a few ways. One method includes reacting methyl salicylate with nitrous acid in the presence of light

Formula: C₈H₇NO₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 197.14 g/mol

Ref: 3D-FM37814

Methyl 2-hydroxy-5-nitrobenzoate

CAS: 17302-46-4

Formula: C₈H₇NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 197.146

Ref: 10-F222455

5-Nitrosalicylic Acid Methyl Ester

Controlled Product

CAS: 17302-46-4

Applications 5-Nitrosalicylic Acid Methyl Ester is an salicylic acid derivative with anti-inflammatory effect against colitis.
References Kim, J.H., et al.: Euro. J. Med. Chem., 48, 36 (2012);

Formula: C₈H₇NO₅

Color and Shape: Neat

Molecular weight: 197.14

Ref: TR-N520915