CAS 17303-67-2

Goniothalamin

Description:

Goniothalamin is a naturally occurring chemical compound classified as an alkaloid, primarily extracted from the plant species Goniothalamus. It is known for its diverse biological activities, including anti-cancer, anti-inflammatory, and antimicrobial properties. The molecular structure of goniothalamin features a complex arrangement that includes a bicyclic core, contributing to its pharmacological effects. It has been the subject of various studies aimed at understanding its mechanism of action and potential therapeutic applications. Goniothalamin exhibits moderate solubility in organic solvents, which is typical for many alkaloids, and its stability can be influenced by environmental factors such as pH and temperature. Research into goniothalamin continues to explore its potential as a lead compound in drug development, particularly in oncology, due to its ability to induce apoptosis in cancer cells. Overall, goniothalamin represents a significant interest in natural product chemistry and pharmacology, highlighting the importance of plant-derived compounds in medicinal research.

Formula: C₁₃H₁₂O₂

InChI: InChI=1S/C13H12O2/c14-13-8-4-7-12(15-13)10-9-11-5-2-1-3-6-11/h1-6,8-10,12H,7H2/b10-9+/t12-/m1/s1

InChI key: InChIKey=RLGHFVLWYYVMQZ-BZYZDCJZSA-N

SMILES: C(=C/C1=CC=CC=C1)\[C@@H]2OC(=O)C=CC2

Synonyms:

• (+)-(R)-Goniothalamin
• (6R)-(+)-5,6-Dihydro-6-styryl-2-pyrone
• (6R)-(+)-Goniothalamin
• (6R)-5,6-Dihydro-6-[(1E)-2-phenylethenyl]-2H-pyran-2-one
• (6R)-6-[(E)-2-phenylethenyl]-5,6-dihydro-2H-pyran-2-one
• 2H-Pyran-2-one, 5,6-dihydro-6-(2-phenylethenyl)-, (S-(E))- (9CI)
• 2H-Pyran-2-one, 5,6-dihydro-6-(2-phenylethenyl)-, [R-(E)]-
• 2H-Pyran-2-one, 5,6-dihydro-6-[(1E)-2-phenylethenyl]-, (6R)-
• 2H-Pyran-2-one, 5,6-dihydro-6-styryl-, (5S)-(+)-
• Ccris 9005
• Goniothalamine

Goniothalamin

CAS: 17303-67-2

Formula: C₁₃H₁₂O₂

Purity: 98.0%

Molecular weight: 200.2332

Ref: IN-DA00AKX9

Goniothalamin

CAS: 17303-67-2

Goniothalamin

Purity: 98%

Ref: 54-OR1037134

Goniothalamin

CAS: 17303-67-2

Goniothalamin induces apoptosis in various cancer cell lines and has gastroprotective activity.

Formula: C₁₃H₁₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 200.23

Ref: TM-TN4160

Goniothalamin

CAS: 17303-67-2

Formula: C₁₃H₁₂O₂

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 200.237

Ref: BP-SBP02513

Goniothalamin

CAS: 17303-67-2

Goniothalamin is a bioactive styryl-lactone, which is a naturally occurring compound derived from the Goniothalamus plant species, commonly found in Southeast Asia. It is recognized for its intriguing biological properties, particularly its potential anticancer effects. Goniothalamin exerts its mode of action primarily through the induction of apoptosis in cancerous cells. It initiates cell death by disrupting mitochondrial membrane potential, activating caspase enzymes, and promoting the release of cytochrome c into the cytosol. Additionally, it is reported to modulate various signaling pathways involved in cell survival and proliferation.

Formula: C₁₃H₁₂O₂

Purity: Min. 95%

Molecular weight: 200.23 g/mol

Ref: 3D-SAA30367