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CAS 17318-03-5

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3-FLUOROPHENYLMAGNESIUM BROMIDE

Description:
3-Fluorophenylmagnesium bromide is an organomagnesium compound, specifically a Grignard reagent, characterized by its reactivity and utility in organic synthesis. It features a phenyl group substituted with a fluorine atom at the meta position, which influences its electronic properties and reactivity. As a Grignard reagent, it is highly nucleophilic, allowing it to react with various electrophiles, including carbonyl compounds, to form alcohols after hydrolysis. The presence of the fluorine atom can enhance the reactivity of the compound due to its electronegative nature, which can stabilize the negative charge on the carbon atom during reactions. This compound is typically handled under anhydrous conditions, as it reacts vigorously with water and moisture, leading to the formation of the corresponding hydrocarbon and magnesium hydroxide. Its applications are primarily in the synthesis of complex organic molecules, making it valuable in pharmaceutical and materials chemistry. Safety precautions are essential when working with this reagent due to its flammability and reactivity.
Formula:C6H4BrFMg
InChI:InChI=1/C6H4F.BrH.Mg/c7-6-4-2-1-3-5-6;;/h1-2,4-5H;1H;/q;;+1/p-1/rC6H4BrFMg/c7-9-6-3-1-2-5(8)4-6/h1-4H
SMILES:c1ccc(cc1)F.Br.[Mg]
Synonyms:
  • 3-Fluorophenylmagnesium Bromide, 0.5M Solu Tion In Tetrahydrofuran
  • 3-Fluorophenylmagnesium Bromide, 1.0M So
  • Bromo(3-Fluorophenyl)Magnesium
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