CAS 1732-29-2

8-Hydroxy-1-nitropyrene

Description:

8-Hydroxy-1-nitropyrene is an organic compound that belongs to the class of nitroaromatic compounds, specifically a derivative of pyrene. It features a hydroxyl group (-OH) and a nitro group (-NO2) attached to the pyrene structure, which is a polycyclic aromatic hydrocarbon. This compound is characterized by its potential as a pollutant and its relevance in environmental chemistry, particularly in studies related to air quality and the effects of polycyclic aromatic hydrocarbons (PAHs). 8-Hydroxy-1-nitropyrene is known for its mutagenic and carcinogenic properties, making it a subject of interest in toxicology and public health research. Its solubility and stability can vary depending on environmental conditions, influencing its behavior in biological systems and ecosystems. Analytical methods such as chromatography and mass spectrometry are often employed to detect and quantify this compound in various matrices, including environmental samples. Understanding its characteristics is crucial for assessing its environmental impact and potential health risks associated with exposure.

Formula: C₁₆H₉NO₃

InChI: InChI=1/C16H9NO3/c18-14-8-4-10-2-1-9-3-7-13(17(19)20)11-5-6-12(14)16(10)15(9)11/h1-8,18H

InChI key: InChIKey=RHXGKMNLLUKFLG-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C2C3=C4C(C=C2)=C(O)C=CC4=CC=C3C=C1

Synonyms:

• 1-Hydroxy-8-nitropyrene
• 1-Nitro-8-Hydroxypyrene
• 1-Nitropyren-8-Ol
• 1-Pyrenol, 8-nitro-
• 8-Hydroxy-1-Nitropyrene
• 8-Nitro-1-pyrenol
• 8-Nitropyren-1-Ol
• 8-Nitropyrene-1-ol
• 1-nitropyrene-8-ol
• DISCONTINUED. Please see N519995

1-Pyrenol, 8-nitro-

CAS: 1732-29-2

Formula: C₁₆H₉NO₃

Molecular weight: 263.2476

Ref: IN-DA001YPD

6-Nitro-1-pyrenol and 8-Nitro-1-pyrenol Mixture (8-Nitro major)

Controlled Product

CAS: 1732-29-2, 1767-28-8

Applications 6-Nitro-1-pyrenol and 8-Nitro-1-pyrenol are urinary hydroxylated metabolites used as a biomarkers of exposure to polycyclic aromatic hydrocarbons.
References Toriba, A., et al.: J. Health. Sci., 53; 631 (2007); Chae, Y.H., et al.: Cancer Res., 59, 1473 (1999);

Formula: C₁₆H₉NO₃

Color and Shape: Neat

Molecular weight: 263.25

Ref: TR-N519995

8-Nitro-1-pyrenol-d8 (~85%)

Controlled Product

CAS: 1732-29-2

Applications 8-Nitro-1-pyrenol is a urinary hydroxylated metabolites used as a biomarkers of exposure of polycyclic aromatic hydrocarbons. This is the labeled analog.
References Toriba, A., et al.: J. Health. Sci., 53; 631 (2007); Chae, Y.H., et al.: Cancer Res., 59, 1473 (1999); Sangaiah, R., et al.: Poly. Aro. Comp., 11, 283 (1996);

Formula: C₁₆HD₈NO₃

Purity: ~85%

Color and Shape: Neat

Molecular weight: 271.39

Ref: TR-N519992

8-Nitro-1-pyrenol-d8

CAS: 1732-29-2

8-Nitro-1-pyrenol-d8 is a potent inhibitor of cancer cells that has been used in medicinal research. This compound inhibits the activity of proteins involved in cell cycle regulation and promotes apoptosis, making it a promising candidate for anticancer therapies. 8-Nitro-1-pyrenol-d8 has been found to be effective against various types of human cancer, including leukemia. This compound has also been shown to inhibit the activity of kinases that are involved in tumor growth and progression. Additionally, 8-Nitro-1-pyrenol-d8 can be detected in urine samples, making it a useful tool for studying the effects of cancer inhibitors on the body. Overall, this compound shows great potential as an anticancer agent and warrants further investigation in the field of oncology.

Formula: C₁₆H₉NO₃

Purity: Min. 95%

Molecular weight: 263.25 g/mol

Ref: 3D-BAA73229