CAS 17320-10-4: 4β-Hydroxycholesterol
Description:4β-Hydroxycholesterol is a sterol compound that is a derivative of cholesterol, characterized by the presence of a hydroxyl group at the 4β position of the steroid nucleus. This compound is of interest in biochemistry and pharmacology due to its role in cholesterol metabolism and its potential implications in various physiological processes. It is produced in the body through the enzymatic action of cytochrome P450 enzymes, particularly CYP3A4. 4β-Hydroxycholesterol has been studied for its effects on cholesterol homeostasis and its potential as a biomarker for cholesterol synthesis. It is generally found in low concentrations in human plasma and is thought to influence lipid metabolism and inflammatory responses. The compound is also being investigated for its potential role in cardiovascular health and disease. As with many sterols, its solubility is limited in water but it can be dissolved in organic solvents. Safety and handling precautions should be observed when working with this compound, as with all chemical substances.
Formula:C27H46O2
InChI:InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)20-11-12-21-19-9-10-23-25(29)24(28)14-16-27(23,5)22(19)13-15-26(20,21)4/h10,17-22,24-25,28-29H,6-9,11-16H2,1-5H3/t18-,19+,20-,21+,22+,24+,25-,26-,27-/m1/s1
InChI key:InChIKey=CZDKQKOAHAICSF-JSAMMMMSSA-N
SMILES:OC1C2=CCC3C(CCC4(C)C(CCC34)C(C)CCCC(C)C)C2(C)CCC1O
- Synonyms:
- (3β,4β)-Cholest-5-ene-3,4-diol
- 3β,4β-Dihydroxycholest-5-ene
- 4β-Hydroxycholesterol
- 5-Cholesten-3-Beta, 4-Beta-Diol
- Cholest-5-Ene-3,4-Diol
- Cholest-5-ene-3,4-diol, (3β,4β)-
- Cholest-5-ene-3β,4β-diol
- cis-3,4-Dihydroxy-Δ<sup>5</sup>-cholestene
- cis-Δ<sup>5</sup>-Cholestene-3,4-diol