CAS 17321-77-6
:clomipramine hydrochloride
Description:
Clomipramine hydrochloride is a tricyclic antidepressant primarily used in the treatment of obsessive-compulsive disorder (OCD) and other mood disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly serotonin and norepinephrine, thereby enhancing their availability in the synaptic cleft. This compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration. Clomipramine hydrochloride has a relatively long half-life, which allows for once-daily dosing in many cases. Its pharmacological profile includes a range of side effects, such as sedation, dry mouth, and potential cardiovascular effects, necessitating careful monitoring in patients. The substance is classified as a prescription medication and is subject to regulatory controls due to its potential for side effects and interactions with other drugs. Overall, clomipramine hydrochloride is an important therapeutic agent in psychiatry, particularly for patients with treatment-resistant OCD.
Formula:C19H24Cl2N2
InChI:InChI=1/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
InChI key:InChIKey=WIMWMKZEIBHDTH-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=C(Cl)C2.Cl
Synonyms:- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
- 3-Chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
- 3-Chloroimipramine hydrochloride
- 5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
- 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- Anafranil
- Anaphranil
- Anatranil
- Chlorimipramine hydrochloride
- Chloroimipram-ine HCl
- Chloroimipramine monohydrochloride
- Clomipramine HCl
- ANAFRANIL HYDROCHLORIDE
- 5H-Dibenzb,fazepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
- CLOMIPRAMINE HYDROCHLORIDE
- Clomipraminhydrochlorid
- 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride
- Chlomipramine
- 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5h-dibenz[b,f]azepine monohydrochloride
- 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5h-dibenz(b,f)azepinemono
- 3-CHLORO-10,11-DIHYDRO-N,N-DIMETHYL-5H-DIBENZ[B,F]AZEPINE-5-PROPANAMINE HYDROCHLORIDE
- f)azepine,10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5h-dibenz(mon
- f)azepine-5-propanamine,3-chloro-10,11-dihydro-n,n-dimethyl-5h-dibenz(mo
- CLOMIPRAMINE HYDROCHLORIDE \ SEROTONIN U PTAKE INHIBITOR, ANTIDEPRESSANT
- 3-chloroimipraminehydrochloride
- CHLOROIMIPRAMINE HYDROCHLORIDE
- See more synonyms
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Found 23 products.
Clomipramine hydrochloride
CAS:Potent, selective 5-HT uptake blockerFormula:C19H24Cl2N2Color and Shape:White to pale yellow, Crystals or crystalline powderMolecular weight:351.32Clomipramine hydrochloride
CAS:Clomipramine hydrochlorideFormula:C19H23ClN2HClPurity:99.6%Color and Shape:White To Off-WhiteMolecular weight:350.13165Clomipramine Hydrochloride
CAS:Antidepressants, tranquilizers and other psychotherapeuFormula:C19H23ClN2·HCIColor and Shape:White Yellow PowderMolecular weight:454.06727(3-{5-chloro-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl}propyl)dimethylamine hydrochloride
CAS:Formula:C19H24Cl2N2Purity:99%Color and Shape:SolidMolecular weight:351.3133Clomipramine Hydrochloride
CAS:Clomipramine HydrochlorideFormula:C19H23ClN2HClPurity:>99%Color and Shape:SolidMolecular weight:351.31Clomipramine hydrochloride
CAS:Clomipramine HCl (Anafranil) is a serotonin-inhibiting tricyclic antidepressant, well-absorbed and metabolized to desmethylclomipramine in the liver.Formula:C19H23ClN2·HClPurity:99.04% - 99.47%Color and Shape:SolidMolecular weight:351.31Clomipramine-13C-d3 HCl
CAS:Formula:C1813CH20D3ClN2·HClColor and Shape:White To Off-White SolidMolecular weight:318.87 36.46Clomipramine HCl
CAS:Formula:C19H23ClN2·HClColor and Shape:Off-White SolidMolecular weight:314.86 36.46Clomipramine hydrochloride
CAS:Clomipramine hydrochlorideFormula:C19H23ClN2·HClPurity:≥98%Molecular weight:351.31Clomipramine Hydrochloride (Standard)
CAS:Clomipramine Hydrochloride (Standard) is the standard substance of Clomipramine Hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.Formula:C19H23ClN2·HClColor and Shape:SolidMolecular weight:351.31Clomipramine Hydrochloride
CAS:Formula:C19H23ClN2·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:351.32Clomipramine Hydrochloride
CAS:Controlled ProductFormula:C19H23ClN2·ClHColor and Shape:NeatMolecular weight:351.31Clomipramine hydrochloride
CAS:Formula:C19H23ClN2·HClPurity:98.0 - 102.0 % (dried basis)Color and Shape:White or almost white crystalline powderMolecular weight:351.32Clomipramine Hydrochloride
CAS:Controlled ProductApplications Serotonin reuptake inhibitor. Antidepressant; antiobsessional agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Peters, M.D., et al.: Clin. Pharm., 9, 165 (1990), Adamczyk, M., et al.: Ther. Drug Monit., 17, 371 (1995), Poolsup, N., et al.: J. Clin. Pharm. Ther., 25, 197 (2000), Bose, D., et al.: J. Pharmacol. Toxicol. Methods, 52, 323 (2005),Formula:C19H23ClN2·ClHColor and Shape:NeatMolecular weight:351.31Clomipramine hydrochloride - Bio-X ™
CAS:Controlled ProductClomipramine is a tricyclic antidepressant drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine. It is used to treat obsessive compulsive disorder, panic disorders and cataplexy. Additionally, Clomipramine is shown to modulate immune activation and shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro-inflammatory cytokines.
Formula:C19H24Cl2N2Purity:Min. 95%Color and Shape:White PowderMolecular weight:351.31 g/molClomipramine hydrochloride
CAS:Controlled ProductClomipramine hydrochloride is the hydrochloride salt form of clomipramine, an amphiphilic drug, derivative of dibenzazepine. It is presumed that this tricyclic compound affects serotonin uptake in the brain increasing thus the activity of serotonin. Also, clomipramine reduces the re-uptake of norepinephrine (active metabolite desmethylclomipramine) and binds to alpha-adrenergic, histaminergic, and cholinergic receptors (side effects). Clomipramine is antidepressant, used to treat obsessive compulsive disorder, panic disorders and cataplexy. Clomipramine is shown to modulate immune activation, shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro- inflammatory cytokines. Clomipramine could be a good candidate to counteract SARS-CoV-2 infection worsening thanks to its high penetration in the brain and its anti-inflammatory effects.Formula:C19H24Cl2N2Purity:Min. 95%Color and Shape:SolidMolecular weight:351.31 g/mol
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