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CAS 17321-77-6

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clomipramine hydrochloride

Description:
Clomipramine hydrochloride is a tricyclic antidepressant primarily used in the treatment of obsessive-compulsive disorder (OCD) and other mood disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly serotonin and norepinephrine, thereby enhancing their availability in the synaptic cleft. This compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration. Clomipramine hydrochloride has a relatively long half-life, which allows for once-daily dosing in many cases. Its pharmacological profile includes a range of side effects, such as sedation, dry mouth, and potential cardiovascular effects, necessitating careful monitoring in patients. The substance is classified as a prescription medication and is subject to regulatory controls due to its potential for side effects and interactions with other drugs. Overall, clomipramine hydrochloride is an important therapeutic agent in psychiatry, particularly for patients with treatment-resistant OCD.
Formula:C19H24Cl2N2
InChI:InChI=1/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22;/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3;1H
InChI key:InChIKey=WIMWMKZEIBHDTH-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=C(Cl)C2.Cl
Synonyms:
  • 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
  • 3-Chloro-5-(3-dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
  • 3-Chloroimipramine hydrochloride
  • 5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
  • 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
  • 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-, monohydrochloride
  • Anafranil
  • Anaphranil
  • Anatranil
  • Chlorimipramine hydrochloride
  • See more synonyms
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products per page.Found 22 products.
  • Clomipramine hydrochloride
    Biosynth
    + Info

    Clomipramine hydrochloride

    Controlled Product
    CAS:
    <p>Clomipramine hydrochloride is the hydrochloride salt form of clomipramine, an amphiphilic drug, derivative of dibenzazepine. It is presumed that this tricyclic compound affects serotonin uptake in the brain increasing thus the activity of serotonin. Also, clomipramine reduces the re-uptake of norepinephrine (active metabolite desmethylclomipramine) and binds to alpha-adrenergic, histaminergic, and cholinergic receptors (side effects). Clomipramine is antidepressant, used to treat obsessive compulsive disorder, panic disorders and cataplexy. Clomipramine is shown to modulate immune activation, shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro- inflammatory cytokines. Clomipramine could be a good candidate to counteract SARS-CoV-2 infection worsening thanks to its high penetration in the brain and its anti-inflammatory effects.</p>
    Formula:C19H24Cl2N2
    Purity:Min. 95%
    Color and Shape:Solid
    Molecular weight:351.31 g/mol

    Ref: 3D-FC20505

    5g
    194.00€
    10g
    310.00€
    25g
    485.00€
    50g
    728.00€
    100g
    886.00€
  • Clomipramine hydrochloride - Bio-X ™
    Biosynth
    + Info

    Clomipramine hydrochloride - Bio-X ™

    Controlled Product
    CAS:
    <p>Clomipramine is a tricyclic antidepressant drug that inhibits the reuptake of serotonin, norepinephrine, and dopamine. It is used to treat obsessive compulsive disorder, panic disorders and cataplexy. Additionally, Clomipramine is shown to modulate immune activation and shows constant anti-inflammatory properties at therapeutic concentrations by consistently decreasing pro-inflammatory cytokines.</p>
    Formula:C19H24Cl2N2
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:351.31 g/mol

    Ref: 3D-BC164325

    100mg
    134.00€