CAS 17331-13-4

2'-Deoxy-N2-Dimethylaminomethylene-Guanosine

Description:

2'-Deoxy-N2-Dimethylaminomethylene-Guanosine, with the CAS number 17331-13-4, is a modified nucleoside that features a guanine base linked to a deoxyribose sugar. This compound is characterized by the presence of a dimethylaminomethylene group at the N2 position of the guanine, which enhances its chemical reactivity and potential biological activity. The modification can influence its interactions with nucleic acids, potentially affecting processes such as transcription and translation. As a nucleoside analog, it may exhibit unique properties in terms of binding affinity to nucleic acid structures and could be of interest in medicinal chemistry and molecular biology research. The presence of the dimethylamino group may also impart basicity, affecting solubility and stability in various environments. Overall, this compound represents a valuable tool for studying nucleic acid behavior and could have implications in drug development and therapeutic applications.

Synonyms:

• 2'-Deoxy-N2-Dimethylaminomethylen-Guanosine
• DMF-dG

Guanosine, 2'-deoxy-N-[(dimethylamino)methylene]-

CAS: 17331-13-4

Formula: C₁₃H₁₈N₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 322.3198

Ref: IN-DA001YRZ

2''-Deoxy-N2-DMF-guanosine

CAS: 17331-13-4

Ref: 7W-GN5490

N'-(9-((2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-yl)-6-Oxo-6,9-Dihydro-1H-Purin-2-yl)-N,N-Dimethylformimidamide

CAS: 17331-13-4

N'-(9-((2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Tetrahydrofuran-2-yl)-6-Oxo-6,9-Dihydro-1H-Purin-2-yl)-N,N-Dimethylformimidamide

Purity: 95%

Molecular weight: 322.32g/mol

Ref: 54-OR1028123

2'-Deoxy-N2-DMF-guanosine

CAS: 17331-13-4

2'-Deoxy-N2-DMF-guanosine is a synthetic nucleoside that is used as a primer in DNA sequencing and hybridization experiments. It binds to the 5' end of single-stranded DNA and is complementary to guanosine. The 2'-deoxy group on the sugar moiety prevents the formation of hydrogen bonds with other bases, which increases stability. In addition, it has a high affinity for dna binding proteins. This synthetic nucleoside has been shown to be useful in clinical diagnostics and can be used as a probe for detecting diazirine residues in DNA sequences.

Formula: C₁₃H₁₈N₆O₄

Purity: Min. 97 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 322.33 g/mol

Ref: 3D-ND10841

Dmf-dg

CAS: 17331-13-4

Purity: 98%

Color and Shape: Solid

Molecular weight: 322.325

Ref: 10-F988172

Dmf-dg

CAS: 17331-13-4

Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a nucleoside of deoxyguanosine (dG) with a dimethylaminomethylene (DMF) base protection, employed in the synthesis of oligonucleotides.

Formula: C₁₃H₁₈N₆O₄

Color and Shape: Solid

Molecular weight: 322.32

Ref: TM-TSW-00950