Z-Tyr-Leu-NH2, also known as Z-Tyrosyl-Leucine amide, is a synthetic peptide derivative characterized by the presence of a protective Z (benzyloxycarbonyl) group on the tyrosine residue and an amide group at the C-terminus. This compound is typically used in biochemical research and peptide synthesis due to its structural features that enhance stability and solubility. The Z group serves to protect the amino group of tyrosine during synthesis, allowing for selective reactions. The presence of the leucine residue contributes to the hydrophobic character of the peptide, which can influence its interactions with biological membranes and proteins. Z-Tyr-Leu-NH2 may exhibit biological activity, potentially acting as a substrate or inhibitor in enzymatic reactions. Its CAS number, 17331-91-8, allows for precise identification in chemical databases. Overall, Z-Tyr-Leu-NH2 is a valuable compound in the study of peptide chemistry and its applications in drug development and molecular biology.

Z-Tyr-Leu-NH2

17331-91-8: Z-Tyr-Leu-NH2, also known as Z-Tyrosyl-Leucine amide, is a synthetic peptide derivative characterized by the presence of a protective Z (benzyloxycarbonyl) group on the tyrosine residue and an amide group at the C-terminus. This compound is typically used in biochemical research and peptide synthesis due to its structural features that enhance stability and solubility. The Z group serves to protect the amino group of tyrosine during synthesis, allowing for selective reactions. The presence of the leucine residue contributes to the hydrophobic character of the peptide, which can influence its interactions with biological membranes and proteins. Z-Tyr-Leu-NH2 may exhibit biological activity, potentially acting as a substrate or inhibitor in enzymatic reactions. Its CAS number, 17331-91-8, allows for precise identification in chemical databases. Overall, Z-Tyr-Leu-NH2 is a valuable compound in the study of peptide chemistry and its applications in drug development and molecular biology.

<p>The compound Z-Tyr-Leu-NH2 is a synthetic molecule that inhibits the activity of metalloproteases. It binds to the active site of these enzymes, preventing them from cleaving their substrates. The enzyme's activity is inhibited by binding to uncharged amino acid residues in the active site, which prevents attack by the metal ion and therefore prevents cleavage of substrate proteins. Z-Tyr-Leu-NH2 has been shown to be effective against proteases that are involved in Alzheimer's disease and other neurodegenerative diseases. The optimal pH for this compound is 7.5, with a reaction time of 1 hour at 37 degrees Celsius. The transition temperature for this compound is -10 degrees Celsius, with a phase transition at -4 degrees Celsius.</p>

CAS 17331-91-8

Z-Tyr-Leu-NH2

Z-Tyr-Leu-NH2

Ref: 3D-FT111547