CAS 17365-01-4

Etiroxate

Description:

Etiroxate, with the CAS number 17365-01-4, is a chemical compound primarily recognized for its use in the pharmaceutical industry. It is classified as an antiprotozoal agent, often utilized in the treatment of various parasitic infections. The compound exhibits a unique molecular structure that contributes to its biological activity, specifically targeting protozoan parasites. Etiroxate is known for its mechanism of action, which involves inhibiting the growth and reproduction of these pathogens. In terms of physical properties, it is typically presented as a crystalline solid, with solubility characteristics that may vary depending on the solvent used. The compound's stability and reactivity are influenced by environmental factors such as pH and temperature. Safety data indicates that, like many pharmaceuticals, it should be handled with care, adhering to appropriate safety guidelines to mitigate any potential risks associated with exposure. Overall, Etiroxate represents a significant compound in the realm of medicinal chemistry, particularly in the context of treating infectious diseases.

Formula: C₁₈H₁₇I₄NO₄

InChI: InChI=1S/C18H17I4NO4/c1-3-26-17(25)18(2,23)8-9-4-13(21)16(14(22)5-9)27-10-6-11(19)15(24)12(20)7-10/h4-7,24H,3,8,23H2,1-2H3

InChI key: InChIKey=LWZCMKGGFONJPB-UHFFFAOYSA-N

SMILES: O(C1=C(I)C=C(CC(C(OCC)=O)(C)N)C=C1I)C2=CC(I)=C(O)C(I)=C2

Synonyms:

• 17365-01-4
• <span class="text-smallcaps">DL</span>-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester
• <span class="text-smallcaps">DL</span>-α-Methylthyroxine ethyl ester
• Cg 635
• D,L-a-Methylthyroxine Ethyl Ester
• Ethyl O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-alpha-methyltyrosinate
• Etiroxate [INN]
• O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-a-methyltyrosine Ethyl Ester
• Thyroxine, α-methyl-, ethyl ester, <span class="text-smallcaps">DL</span>-
• Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-α-methyl-, ethyl ester
• a-Methyl-DL-thyroxine Ethyl Ester
• tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-alpha-methyl-, ethyl ester
• Thyroxine, α-methyl-, ethyl ester, DL-
• DL-α-Methylthyroxine ethyl ester

Etiroxate

CAS: 17365-01-4

Formula: C₁₈H₁₇I₄NO₄

Color and Shape: Solid

Molecular weight: 818.9498

Ref: IN-DA001Z3S

Etiroxate

Controlled Product

CAS: 17365-01-4

Applications Derivative of thyroxine. Antilipemic.
References Banz, H., et al.: Fortschr. Med., 97, 1942 (1979),

Formula: C₁₈H₁₇I₄NO₄

Color and Shape: Neat

Molecular weight: 818.95

Ref: TR-E932980

Etiroxate

CAS: 17365-01-4

Etiroxate is a fatty acid that inhibits the activity of cholesterol acyltransferase (CAT) and 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) in the liver. It is used as an antileukemic agent, mainly in patients with acute myelogenous leukemia. Etiroxate has been shown to be effective against psychiatric disorders, such as schizophrenia and depression, in double-blind cross-over studies on animals. Etiroxate also has a beneficial effect on cardiac function and hyperlipoproteinemia in humans. Etiroxate suppresses symptoms of these conditions by inhibiting the activity of HMGCR and CAT.

Formula: C₁₈H₁₇I₄NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 818.95 g/mol

Ref: 3D-FE23191

Etiroxate

CAS: 17365-01-4

Etiroxate (CG-635) is a lipid-lowering agent utilized in hyperlipoproteinemia studies [1].

Formula: C₁₈H₁₇I₄NO₄

Color and Shape: Solid

Molecular weight: 818.95

Ref: TM-T82434