CAS 1737-62-8

4-Fluorophenoxyacetic acid hydrazide

Description:

4-Fluorophenoxyacetic acid hydrazide is an organic compound characterized by its hydrazide functional group attached to a phenoxyacetic acid moiety, with a fluorine atom substituted on the phenyl ring. This compound typically appears as a solid and is soluble in polar organic solvents. It exhibits properties typical of hydrazides, including the ability to form hydrogen bonds, which can influence its reactivity and interactions with other molecules. The presence of the fluorine atom can enhance the compound's lipophilicity and may affect its biological activity, making it of interest in pharmaceutical research. 4-Fluorophenoxyacetic acid hydrazide may also participate in various chemical reactions, such as acylation and condensation, due to the reactive nature of the hydrazide group. Its applications may extend to agrochemicals or as an intermediate in the synthesis of more complex organic compounds. As with any chemical substance, safety precautions should be observed when handling it, considering potential toxicity and environmental impact.

Formula: C₈H₉FN₂O₂

InChI: InChI=1/C8H9FN2O2/c9-6-1-3-7(4-2-6)13-5-8(12)11-10/h1-4H,5,10H2,(H,11,12)

SMILES: c1cc(ccc1F)OCC(=NN)O

Synonyms:

• Akos B015229
• Akos Au36-M58
• 2-(4-Fluorophenoxy)Acetic Acid Hydrazide
• 2-(4-Fluorophenoxy)Acetohydrazide

Acetic acid, 2-(4-fluorophenoxy)-, hydrazide

CAS: 1737-62-8

Formula: C₈H₉FN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 184.1677

Ref: IN-DA001Z56

4-Fluorophenoxyacetic acid hydrazide

CAS: 1737-62-8

4-Fluorophenoxyacetic acid hydrazide

Formula: C₈H₉FN₂O₂

Purity: 98%

Color and Shape: White Solid

Molecular weight: 184.17g/mol

Ref: 54-PC4050

4-Fluorophenoxyacetic acid hydrazide

CAS: 1737-62-8

4-Fluorophenoxyacetic acid hydrazide (4FPAAH) is a palladium complex with anti-cancer activity. It induces apoptosis, or programmed cell death, in myelogenous leukemia cells and breast cancer cells. 4FPAAH has been shown to bind to the ATP binding site of the catalytic domain of topoisomerase II on DNA and inhibit its activity. The molecular modeling studies show that 4FPAAH binds in the same way as cisplatin, which is a platinum-based drug commonly used for cancer treatment. The structural analysis shows that 4FPAAH binds to the nitrogen atoms of the protein and eliminates the possibility of any hydrogen bonding interactions. This mechanism may be due to an electrostatic interaction between the positively charged nitrogen atom in 4FPAAH and negative charge on topoisomerase II's active site.

Formula: C₈H₉FN₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 184.17 g/mol

Ref: 3D-FF38787

2-(4-Fluorophenoxy)acetohydrazide

CAS: 1737-62-8

Formula: C₈H₉FN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 184.17

Ref: 10-F012424