CAS 17391-18-3

Corynoxine B

Description:

Corynoxine B is a chemical compound classified as an alkaloid, primarily derived from the plant species of the genus Corynanthe, which is known for its traditional medicinal uses. It is characterized by its complex structure, featuring a bicyclic framework that contributes to its biological activity. Corynoxine B exhibits various pharmacological properties, including potential neuroprotective effects and interactions with neurotransmitter systems, which have garnered interest in the field of medicinal chemistry. The compound is typically studied for its effects on the central nervous system and may have implications in treating conditions such as depression or neurodegenerative diseases. Its solubility and stability can vary depending on the solvent and environmental conditions, which are important factors in its application and study. As with many alkaloids, Corynoxine B may also exhibit toxicity at certain concentrations, necessitating careful handling and thorough investigation in research settings. Overall, Corynoxine B represents a significant area of interest in natural product chemistry and pharmacology.

Formula: C₂₂H₂₈N₂O₄

Synonyms:

• 7-Isocorynoxine
• Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'R,6'S,7'S,8'aS)-
• Corynoxine B, 99.5%
• Corynoxine B
• (7R,16E)-17-Methoxy-2-oxo-20betaH-corynox-16-en-16-carbonsae

Corynoxine B

CAS: 17391-18-3

Formula: C₂₂H₂₈N₂O₄

Purity: 99.5%

Molecular weight: 384.4687

Ref: IN-DA00ABNG

Corynoxine B

CAS: 17391-18-3

Formula: C₂₂H₂₈N₂O₄

Molecular weight: 384.48

Ref: 7W-GY4196

Corynoxine B

CAS: 17391-18-3

Corynoxine B (Cory B), a natural alkaloid isolated from Uncaria rhynchophylla (Miq. ), is an autophagy inducer that enhances the activity of Beclin 1/VPS34 complex and increases autophagy by facilitating the interaction between Beclin 1 and HMGB1/2, which may ameliorate Alzheimer's disease. NVP-BAG956 (NVP-BAG956)

Formula: C₂₂H₂₈N₂O₄

Purity: 99.72%

Color and Shape: Solid

Molecular weight: 384.47

Ref: TM-TQ0258

Corynoxine B

CAS: 17391-18-3

Formula: C₂₂H₂₈N₂O₄

Purity: 95%~99%

Molecular weight: 384.476

Ref: BP-BP3102

Corynoxine B

CAS: 17391-18-3

Formula: C₂₂H₂₈N₂O₄

Molecular weight: 384.48

Ref: 4Z-C-503003

Corynoxine b

CAS: 17391-18-3

Natural alkaloid

Formula: C₂₂H₂₈N₂O₄

Purity: ≥ 75.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 384.47

Ref: 5G-83572

Corynoxine B

CAS: 17391-18-3

Corynoxine B is a bioactive compound, specifically an alkaloid, which is derived from the plant Uncaria rhynchophylla, commonly found in traditional Chinese medicine. Its mode of action involves the modulation of autophagy pathways, enhancing the degradation and clearance of damaged proteins and dysfunctional cellular components. This mechanism is crucial in maintaining cellular homeostasis, especially in neurodegenerative conditions.

Formula: C₂₂H₂₈N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 384.47 g/mol

Ref: 3D-FC145220

Corynoxine B

Controlled Product

CAS: 17391-18-3

Formula: C₂₂H₂₈N₂O₄

Color and Shape: Neat

Molecular weight: 384.469

Ref: TR-C214525