CAS 17397-89-6

(+)-Cerulenin

Description:

(+)-Cerulenin is a natural product and a potent inhibitor of fatty acid synthase, primarily derived from the fungus Cephalosporium caerulens. It is characterized by its unique structure, which includes a long-chain fatty acid moiety and a lactone ring, contributing to its biological activity. The compound exhibits a white to pale yellow crystalline appearance and is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), but has limited solubility in water. (+)-Cerulenin is known for its role in biochemical research, particularly in studies related to lipid metabolism and the regulation of fatty acid synthesis. Its mechanism of action involves the inhibition of the enzyme responsible for the synthesis of fatty acids, making it a valuable tool in pharmacological studies and potential therapeutic applications. Additionally, it has been investigated for its antifungal and anticancer properties, highlighting its significance in both medicinal chemistry and biochemistry. As with many bioactive compounds, proper handling and safety precautions are essential due to its biological activity.

Formula: C₁₂H₁₇NO₃

InChI: InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)/b3-2+,6-5+/t10-,11-/m1/s1

InChI key: InChIKey=GVEZIHKRYBHEFX-NQQPLRFYSA-N

SMILES: C(CC/C=C/C/C=C/C)(=O)[C@@H]1[C@H](C(N)=O)O1

Synonyms:

• (2R,3S)-3-[(4E,7E)-1-Oxo-4,7-nonadien-1-yl]-2-oxiranecarboxamide
• (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide
• 2-Oxiranecarboxamide, 3-[(4E,7E)-1-oxo-4,7-nonadien-1-yl]-, (2R,3S)-
• 3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide
• 7,10-Dodecadienamide, 2,3-epoxy-4-oxo-
• Cerulenin
• Cerulenin, Cephalosporium caerulens
• Helicocerin
• Oxiranecarboxamide, 3-(1-oxo-4,7-nonadienyl)-, [2R-[2α,3α(4E,7E)]]-
• Oxiranecarboxamide, 3-[(4E,7E)-1-oxo-4,7-nonadienyl]-, (2R,3S)-
• [2R-[2α,3α(4E,7E)]]-3-(1-Oxonona-4,7-dienyl)oxiran-2-carboxamid
• [2R-[2α,3α(4E,7E)]]-3-(1-oxonona-4,7-dienil)oxirano-2-carboxamida

Cerulenin, 98%

CAS: 17397-89-6

Has antibiotic and antifungal properties; inhibits fatty acid and steroid biosynthesis

Formula: C₁₂H₁₇NO₃

Purity: 98%

Molecular weight: 223.27

Ref: 02-J64538

Oxiranecarboxamide, 3-(1-oxo-4,7-nonadienyl)-, [2R-[2a,3a(4E,7E)]]-

CAS: 17397-89-6

Formula: C₁₂H₁₇NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 223.2683

Ref: IN-DA00HZMM

Cerulenin

CAS: 17397-89-6

Cerulenin

Formula: C₁₂H₁₇NO₃

Purity: 98% (tlc) (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 223.26828g/mol

Ref: 54-BIC1007

Cerulenin

CAS: 17397-89-6

Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the fungus Cephalosporium caeruleus.

Formula: C₁₂H₁₇NO₃

Purity: 98% - 99.52%

Color and Shape: Solid

Molecular weight: 223.27

Ref: TM-TQ0260

Cerulenin

CAS: 17397-89-6

Formula: C₁₂H₁₇NO₃

Purity: ≥ 98%

Color and Shape: White to light-yellow powder

Molecular weight: 223.27

Ref: 7W-GA8298

Cerulenin

CAS: 17397-89-6

Cerulenin is an antifungal antibiotic with action on fatty acid and steroid biosynthesis inhibition and is used for studying lipid metabolism and cancer research.

Formula: C₁₂H₁₇NO₃

Purity: Min. 95%

Molecular weight: 223.27 g/mol

Ref: 3D-FC162600

Cerulenin (Synthetic)

Controlled Product

CAS: 17397-89-6

Formula: C₁₂H₁₇NO₃

Color and Shape: Neat

Molecular weight: 223.268

Ref: TR-C278590