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CAS 173997-05-2

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Nepicastat

Description:
Nepicastat is a chemical compound that functions primarily as a selective inhibitor of the enzyme dopamine β-hydroxylase, which is involved in the biosynthesis of norepinephrine from dopamine. This inhibition can lead to a decrease in norepinephrine levels, making it of interest in the study of various cardiovascular and neurological conditions. Nepicastat has been investigated for its potential therapeutic applications, particularly in the context of hypertension and heart failure, as well as in the modulation of the sympathetic nervous system. The compound is characterized by its specific molecular structure, which includes a unique arrangement of functional groups that contribute to its biological activity. Additionally, Nepicastat has been evaluated in clinical settings for its safety and efficacy, although its use may be limited by side effects or interactions with other medications. As with many pharmacological agents, ongoing research continues to explore its full potential and mechanisms of action within the body.
Formula:C14H15F2N3S
InChI:InChI=1/C14H15F2N3S/c15-9-3-8-4-10(1-2-12(8)13(16)5-9)19-11(6-17)7-18-14(19)20/h3,5,7,10H,1-2,4,6,17H2,(H,18,20)/t10-/m0/s1
InChI key:InChIKey=YZZVIKDAOTXDEB-JTQLQIEISA-N
SMILES:C(N)C=1N([C@@H]2CC=3C(CC2)=C(F)C=C(F)C3)C(=S)NC1
Synonyms:
  • 2H-Imidazole-2-thione, 5-(aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl)-1,3-dihydro-, (S)-
  • 2H-Imidazole-2-thione, 5-(aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-
  • 5-(Aminomethyl)-1-((S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthyl)-4-imidazoline-2-thione
  • 5-(Aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]-1,3-dihydro-2H-imidazole-2-thione
  • 5-(aminomethyl)-1-[(2S)-5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-1,3-dihydro-2H-imidazole-2-thione
  • Nepicastat [INN]
  • Unii-Vpg12K4540
  • Nepicastat
  • Nepicastat
  • (S)-5-(Aminomethyl)-1-(5,7-difluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-1H-imidazole-2(3H)-thione
  • See more synonyms
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Found 3 products.
  • Nepicastat
    Indagoo
    + Info

    Nepicastat

    CAS:
    Formula:C14H15F2N3S
    Molecular weight:295.3508

    Ref: IN-DA001ZD3

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  • Nepicastat
    Targetmol
    + Info

    Nepicastat

    CAS:
    Nepicastat (SYN117) is a potent, BBB-permeable, selective DBH inhibitor with IC50s of 8.5/9 nM in bovine/human.
    Formula:C14H15F2N3S
    Color and Shape:Solid
    Molecular weight:295.35

    Ref: TM-T60633

    25mg
    1,927.00€
    50mg
    2,507.00€
    100mg
    3,168.00€
  • Nepicastat
    Biosynth
    + Info

    Nepicastat

    CAS:

    Inhibitor of dopamine-β-hydroxylase

    Formula:C14H15F2N3S
    Purity:Min. 95%
    Molecular weight:295.35 g/mol

    Ref: 3D-FN103230

    10mg
    305.00€
    50mg
    747.00€