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CAS 174132-31-1

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Fmoc-p-amino-Phe(Boc)-OH

Description:
Fmoc-p-amino-Phe(Boc)-OH, also known as Fmoc-protected p-amino phenylalanine with a Boc (tert-butyloxycarbonyl) protecting group on the amino group, is a compound commonly used in peptide synthesis and medicinal chemistry. It features a phenylalanine backbone, which is an essential amino acid, and is characterized by its two protective groups: the Fmoc group, which is used to protect the amino group during synthesis, and the Boc group, which protects the amine functionality. This compound is typically a white to off-white solid and is soluble in organic solvents like dimethyl sulfoxide (DMSO) and methanol, but less soluble in water. Its structure allows for selective deprotection, enabling the synthesis of peptides with specific sequences. The presence of both Fmoc and Boc groups provides versatility in synthetic applications, making it a valuable intermediate in the development of pharmaceuticals and biologically active compounds. As with many chemical substances, proper handling and safety precautions should be observed due to potential hazards associated with its use.
Formula:C24H22N2O4
InChI:InChI=1/C24H22N2O4/c25-16-11-9-15(10-12-16)13-22(23(27)28)26-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22H,13-14,25H2,(H,26,29)(H,27,28)/t22-/m0/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](Cc1ccc(cc1)N)C(=O)O)O
Synonyms:
  • Fmoc-Phe(4-NHBoc)-OH
  • Fmoc-L-4-aminophe(Boc)
  • Fmoc-L-4-T-Butyloxycarbonylaminophenylalanine
  • 4-[(tert-butoxycarbonyl)amino]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
  • 4-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-phenylalanine
  • Fmoc-4-(Boc-amino)-L-phenylalanine
  • Fmoc-P(Nh-Boc)-L-Phe-Oh
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