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CAS 174148-03-9

:

N-Boc-cis-4-Fmoc-Amino-L-proline

Description:
N-Boc-cis-4-Fmoc-Amino-L-proline is a synthetic amino acid derivative characterized by its unique structural features that include a tert-butyloxycarbonyl (Boc) protecting group and a fluorenylmethyloxycarbonyl (Fmoc) group. This compound is a proline analog, specifically in its cis configuration, which influences its conformational properties and potential applications in peptide synthesis. The Boc group serves to protect the amino group, facilitating selective reactions, while the Fmoc group allows for easy removal under mild basic conditions, making it advantageous in solid-phase peptide synthesis. The presence of the proline backbone contributes to the rigidity and structural integrity of peptides, often enhancing their biological activity. N-Boc-cis-4-Fmoc-Amino-L-proline is utilized in the development of peptide-based therapeutics and research applications, particularly in the study of protein folding and function. Its stability and reactivity make it a valuable building block in the synthesis of complex peptides and other bioactive molecules.
Formula:C25H28N2O6
InChI:InChI=1/C25H28N2O6/c1-25(2,3)33-24(31)27-13-15(12-21(27)22(28)29)26-23(30)32-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,30)(H,28,29)/t15-,21-/m1/s1
SMILES:CC(C)(C)OC(=O)N1C[C@@H](C[C@@H]1C(=O)O)N=C(O)OCC1c2ccccc2c2ccccc12
Synonyms:
  • N-Boc-Cis-4-N-Fmoc-Amino-L-Proline 97
  • 1,2-Pyrrolidinedicarboxylicacid,4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-,1-(1,1-dimethylethyl)ester,(2S,4S)-
  • (2S,4S)-4-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-1,2-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) ester
  • (4S)-1-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-proline
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