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CAS 174532-82-2

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3-Hydroxynevirapine

Description:
3-Hydroxynevirapine is a synthetic derivative of nevirapine, which is an antiretroviral medication used primarily in the treatment of HIV infection. This compound is characterized by the presence of a hydroxyl group at the 3-position of the nevirapine structure, which may influence its pharmacological properties and metabolic stability. It exhibits antiviral activity by inhibiting the reverse transcriptase enzyme, crucial for the replication of HIV. The molecular structure of 3-Hydroxynevirapine contributes to its ability to interact with the viral enzyme, potentially leading to improved efficacy or reduced side effects compared to its parent compound. Additionally, its solubility, stability, and bioavailability are important factors that determine its therapeutic potential. As with many pharmaceutical compounds, the safety profile, including toxicity and side effects, is critical for its use in clinical settings. Ongoing research may further elucidate its role in HIV therapy and its potential advantages over existing treatments.
Formula:C15H14N4O2
InChI:InChI=1S/C15H14N4O2/c1-8-11(20)7-17-14-12(8)18-15(21)10-3-2-6-16-13(10)19(14)9-4-5-9/h2-3,6-7,9,20H,4-5H2,1H3,(H,18,21)
InChI key:InChIKey=DANIONWINZEYME-UHFFFAOYSA-N
SMILES:CC1=C2C(N(C=3C(C(=O)N2)=CC=CN3)C4CC4)=NC=C1O
Synonyms:
  • 6H-Dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-3-hydroxy-4-methyl-
  • 11-Cyclopropyl-5,11-dihydro-3-hydroxy-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one
  • 6H-Pyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one, 11-cyclopropyl-5,11-dihydro-3-hydroxy-4-methyl-
  • 3-Hydroxynevirapine
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Found 3 products.
  • 3-Hydroxy nevirapine
    Glentham
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    3-Hydroxy nevirapine

    CAS:
    Formula:C15H14N4O2
    Purity:≥ 98.0%
    Color and Shape:Off-white to light yellow solid
    Molecular weight:282.30

    Ref: 7W-GN9319

    ne
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  • 3-Hydroxy Nevirapine
    TLC
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    3-Hydroxy Nevirapine

    CAS:
    Formula:C15H14N4O2
    Molecular weight:282.30

    Ref: 4Z-N-2211

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • 3-Hydroxy Nevirapine
    TRC
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    3-Hydroxy Nevirapine

    Controlled Product
    CAS:
    <p>Applications A metabolite of Nevirapine (N391275).<br>References Rettie, A., et al.: J. Biol. Chem., 263, 13733 (1988), Lamson, M., et al.: Biopharm. Drug Dispos., 20, 285 (1999), Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001), Lu, W., et al.: Drug Metab. Dispos., 36, 1624 (2008),<br></p>
    Formula:C15H14N4O2
    Color and Shape:Neat
    Molecular weight:282.30

    Ref: TR-H948630

    1mg
    950.00€
    500µg
    613.00€