CAS 17465-86-0

γ-Cyclodextrin

Description:

γ-Cyclodextrin is a cyclic oligosaccharide composed of eight glucose units linked by α-1,4-glycosidic bonds, forming a toroidal structure. It is a member of the cyclodextrin family, which also includes α- and β-cyclodextrins, and is characterized by its hydrophilic exterior and hydrophobic central cavity. This unique structure allows γ-cyclodextrin to encapsulate various guest molecules, enhancing their solubility and stability, making it valuable in pharmaceutical, food, and cosmetic applications. It is generally recognized as safe (GRAS) and is soluble in water, with its solubility being influenced by pH and temperature. γ-Cyclodextrin exhibits low toxicity and is biodegradable, which contributes to its appeal in various industries. Additionally, it can form inclusion complexes with a wide range of compounds, including drugs, flavors, and fragrances, thereby improving their delivery and efficacy. Its ability to modulate the release of encapsulated substances makes it a useful excipient in drug formulation and a promising agent in controlled release systems.

Formula: C₄₈H₈₀O₄₀

InChI: InChI=1S/C48H80O40/c49-1-9-33-17(57)25(65)41(73-9)82-34-10(2-50)75-43(27(67)19(34)59)84-36-12(4-52)77-45(29(69)21(36)61)86-38-14(6-54)79-47(31(71)23(38)63)88-40-16(8-56)80-48(32(72)24(40)64)87-39-15(7-55)78-46(30(70)22(39)62)85-37-13(5-53)76-44(28(68)20(37)60)83-35-11(3-51)74-42(81-33)26(66)18(35)58/h9-72H,1-8H2/t9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32?,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-/m1/s1

InChI key: InChIKey=GDSRMADSINPKSL-NXDQAORESA-N

SMILES: C(O)[C@@H]1[C@@]2([C@H](O)[C@@H](O)[C@](O1)(O[C@@]3([C@@H](CO)O[C@@](C(O)[C@H]3O)(O[C@@]4([C@@H](CO)O[C@@]([C@H](O)[C@H]4O)(O[C@@]5([C@@H](CO)O[C@@]([C@H](O)[C@H]5O)(O[C@]6([C@H](O)[C@@H](O)[C@@](O[C@]7([C@H](O)[C@@H](O)[C@@](O[C@]8([C@H](O)[C@@H](O)[C@@](O[C@]9([C@H](O)[C@@H](O)[C@@](O2)(O[C@@H]9CO)[H])[H])(O[C@@H]8CO)[H])[H])(O[C@@H]7CO)[H])[H])(O[C@@H]6CO)[H])[H])[H])[H])[H])[H])[H])[H])[H])[H]

Synonyms:

• 2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-Hexadecaoxanonacyclo[36.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26.2^28,31.2^33,36]hexapentacontane, γ-cyclodextrin deriv.
• Cavamax 8 Food
• Cavamax W 8
• Cavamax W 8 Food
• Cavasol W 6
• Cavasol W8
• Celdex C 100
• Celdex G 100
• Ciclooctapentilosa
• Cyclomaltooctaose
• Cyclooctaamylose
• Cyclooctapentylose
• Dexipar γ-100
• Dexy Pearl γ-100
• Rindex C
• Ringdex C
• Stereoisomer of 5,10,15,20,25,30,35,40-octakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol
• Stereoisomer of 5,10,15,20,25,30,35,40-octakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26.2^28,31.2^33,36]hexapentacontane-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecol
• Γ-100
• γ-Cyclodextrine
• γ-Dextrin
• γ-Cyclodextrin

γ-Cyclodextrin

CAS: 17465-86-0

Formula: C₄₈H₈₀O₄₀

Purity: >99.0%(HPLC)

Color and Shape: White powder to crystal

Molecular weight: 1,297.13

Ref: 3B-C0869

GAMMACYCLODEXTRIN CRS

CAS: 17465-86-0

GAMMACYCLODEXTRIN CRS

Formula: C₄₈H₈₀O₄₀

Molecular weight: 1297.125

Ref: 41-G0150000

γ Cyclodextrin

CAS: 17465-86-0

Sugars, chemically pure, other than sucrose, lactose, m

Formula: C₄₈H₈₀O₄₀

Color and Shape: White Powder

Molecular weight: 1297.12

Ref: 45-1154591

γ-Cyclodextrin

CAS: 17465-86-0

Formula: C₄₈H₈₀O₄₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 1297.1248

Ref: IN-DA003AAV

γ-Cyclodextrin

CAS: 17465-86-0

γ-Cyclodextrin

Formula: C₄₈H₈₀O₄₀

Purity: 98%

Color and Shape: white solid

Molecular weight: 1,297.12g/mol

Ref: 54-BIB6136

γ-Cyclodextrin

CAS: 17465-86-0

Formula: C₄₈H₈₀O₄₀·xH₂O

Purity: ≥ 98.0% (dried basis)

Color and Shape: White or almost white powder

Molecular weight: 1297.12 (anhydrous)

Ref: 7W-GC9842

Sugammadex Impurity 1 (Cyclooctapentylose)

CAS: 17465-86-0

Formula: C₄₈H₈₀O₄₀

Color and Shape: White To Off-White Solid

Molecular weight: 1297.13

Ref: 4Z-S-082002

γ-Cyclodextrin

CAS: 17465-86-0

γ-Cyclodextrin (Ringdex C) is a cycloamylose composed of eight alpha-(1->4) linked D-glucopyranose units found in some foods.

Formula: C₄₈H₈₀O₄₀

Purity: 98.56%

Color and Shape: White Solid Crystalline

Molecular weight: 1297.12

Ref: TM-T20682

γ-cyclodextrin

CAS: 17465-86-0

γ-cyclodextrin

Formula: C₄₈H₈₀O₄₀

Molecular weight: 1,297.12g/mol

Ref: 54-BIM1016

γ-Cyclodextrin

CAS: 17465-86-0

Formula: C₄₈H₈₀O₄₀

Molecular weight: 1297.13

Ref: ST-EA-CP-C118003

γ-Cyclodextrin

CAS: 17465-86-0

Stability Hygroscopic
Applications γ-Cyclodextrin is used as nanomolecular encapsulation for drug delivery and pharmaceuticals. Used in the synthesis of unilamellar vesicles.
References Ikeda, A. et al.: Chem. Comm., 50, 1288 (2014); Gudmundsdottir, B. et al.: J. Ocular Pharm. Ther., 30, 35 (2014);

Formula: C₄₈H₈₀O₄₀

Color and Shape: White

Molecular weight: 1297.12

Ref: TR-C989095

γ-Cyclodextrin Deuterated

Controlled Product

CAS: 17465-86-0

Applications γ-Cyclodextrin Deuterated is a labelled version is γ-Cyclodextrin, which is used as nanomolecular encapsulation for drug delivery and pharmaceuticals. Used in the synthesis of unilamellar vesicles.
References Ikeda, A. et al.: Chem. Comm., 50, 1288 (2014); Gudmundsdottir, B. et al.: J. Ocular Pharm. Ther., 30, 35 (2014);

Formula: C₄₈H₈₀O₄₀(Undeuterated)

Color and Shape: Neat

Molecular weight: 1321.27

Ref: TR-C989097

γ-Cyclodextrin

CAS: 17465-86-0

Gamma-cyclodextrin (and its hydrated form) is a cyclic oligosaccharide with 8 D-glucose residues which are α-1,4-linked. Gamma-cyclodextrin is used in the food industry to encapsulate flavors and fragrances. Gamma-cyclodextrin can improve the bioavailability of compounds with low water solubility, such as Coenzyme Q10, which has been used in nutraceuticals. Its cavity size, larger than α- and β-cyclodextrins, allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.

Formula: C₄₈H₈₀O₄₀

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 1,297.12 g/mol

Ref: 3D-OC12106

γ-Cyclodextrin

CAS: 17465-86-0

Formula: C₄₈H₈₀O₄₀

Purity: 96.0%

Color and Shape: Solid, White powder

Molecular weight: 1297.128

Ref: 10-F023231

γ-Cyclodextrin

CAS: 17465-86-0

Formula: C₄₈H₈₀O₄₀

Color and Shape: Neat

Molecular weight: 1297.12

Ref: 04-C11821300