CAS 174756-45-7

4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanol

Description:

4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanol, with CAS number 174756-45-7, is a chemical compound that belongs to the class of thienobenzodiazepines. This substance features a thieno ring fused to a benzodiazepine structure, which contributes to its potential pharmacological properties. The presence of a piperazine moiety enhances its interaction with biological targets, particularly in the central nervous system. The methanol group at the 2-position may influence its solubility and bioavailability. Typically, compounds in this class are investigated for their anxiolytic, sedative, or anticonvulsant effects. The specific characteristics, such as melting point, solubility, and spectral data, would depend on the compound's purity and the conditions under which it is studied. As with many benzodiazepine derivatives, understanding its mechanism of action and potential therapeutic applications would require further research, including in vitro and in vivo studies. Safety and toxicity profiles are also critical for evaluating its suitability for medicinal use.

Formula: C₁₇H₂₀N₄OS

InChI: InChI=1S/C17H20N4OS/c1-20-6-8-21(9-7-20)16-13-10-12(11-22)23-17(13)19-15-5-3-2-4-14(15)18-16/h2-5,10,19,22H,6-9,11H2,1H3

InChI key: InChIKey=FPDIERBPQFAFSI-UHFFFAOYSA-N

SMILES: C(O)C1=CC=2C(=NC=3C(NC2S1)=CC=CC3)N4CCN(C)CC4

Synonyms:

• 10H-Thieno[2,3-b][1,5]benzodiazepine-2-methanol, 4-(4-methyl-1-piperazinyl)-
• 2-Hydroxymethyl Olanzapine-d3
• 4-(4-Methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanol
• 4-[4-(Methyl-d3)-1-piperazinyl]-10H-thieno[2,3-b][1,5]benzodiazepine-2-methanol
• Ly 290411
• [4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepin-2-yl]methanol

LY-290411

CAS: 174756-45-7

LY-290411 is a bioactive chemical.

Formula: C₁₇H₂₀N₄OS

Color and Shape: Solid

Molecular weight: 328.43

Ref: TM-T33009

2-Hydroxymethyl Olanzapine

CAS: 174756-45-7

Formula: C₁₇H₂₀N₄OS

Color and Shape: Brown Solid

Molecular weight: 328.43

Ref: 4Z-O-0133

2-Hydroxymethyl Olanzapine

Controlled Product

CAS: 174756-45-7

Stability Hygroscopic
Applications A minor metabolite of Olanzapine.
References Moore, N., et al.: J. Pharmacol. Exper. Ther., 262, 545 (1992), Chiu, J., et al.: J. Pharmaceut. Biomed. Anal., 14, 609 (1996), Kassahun, K., et al.: Drug Metab. Dispos., 25, 81 (1997),

Formula: C₁₇H₂₀N₄OS

Color and Shape: Neat

Molecular weight: 328.43

Ref: TR-H947780

2-Hydroxymethyl olanzapine

Controlled Product

CAS: 174756-45-7

2-Hydroxymethyl olanzapine is an atypical antipsychotic drug that can be used to treat schizophrenia and other psychotic disorders. The drug is metabolized in the liver and has a linear response in plasma concentrations. It has been shown to have high plasma levels in humans, with a wide range of therapeutic effects. 2-Hydroxymethyl olanzapine has been found to be more effective for women than men, as well as for patients suffering from hyperactivity and psychosis. This drug should not be administered to patients who are experiencing symptoms of schizophrenia or other psychotic disorders. 2-Hydroxymethyl olanzapine is extracted from human liver cells by using organic solvents such as chloroform or dichloromethane. It can also be synthesized from 2-chloroethanol and benzaldehyde through a process of reductive amination.

Formula: C₁₇H₂₀N₄OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 328.43 g/mol

Ref: 3D-FH24394

2-Hydroxymethyl Olanzapine

CAS: 174756-45-7

Formula: C₁₇H₂₀N₄OS

Molecular weight: 328.43

Ref: ST-EA-CP-O1044

10H-Thieno[2,3-b][1,5]benzodiazepine-2-methanol, 4-(4-methyl-1-piperazinyl)-

CAS: 174756-45-7

Formula: C₁₇H₂₀N₄OS

Color and Shape: Solid

Molecular weight: 328.4319

Ref: IN-DA001ZX9