CymitQuimica logo

CAS 175013-84-0

:

TONABERSAT

Description:
Tonabersat, with the CAS number 175013-84-0, is a chemical compound that has been investigated primarily for its potential therapeutic applications, particularly in the context of neurological disorders. It is classified as a selective antagonist of the 2,3-dihydroxy-6-nitro-7-sulfamoylbenzoic acid (NBQX) binding site on the AMPA receptor, which plays a crucial role in excitatory neurotransmission in the central nervous system. Tonabersat has been studied for its neuroprotective properties and its ability to modulate synaptic transmission, making it a candidate for conditions such as epilepsy and other neurodegenerative diseases. The compound is characterized by its specific molecular structure, which contributes to its pharmacological activity. Additionally, its safety profile and efficacy in clinical settings are subjects of ongoing research. As with many investigational drugs, further studies are necessary to fully understand its mechanisms of action, therapeutic potential, and any associated side effects.
Formula:C20H19ClFNO4
InChI:InChI=1/C20H19ClFNO4/c1-10(24)11-5-7-16-13(8-11)17(18(25)20(2,3)27-16)23-19(26)12-4-6-15(22)14(21)9-12/h4-9,17-18,25H,1-3H3,(H,23,26)/t17-,18-/m0/s1
SMILES:CC(=O)c1ccc2c(c1)[C@@H]([C@@H](C(C)(C)O2)O)N=C(c1ccc(c(c1)Cl)F)O
Synonyms:
  • N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-3- chloro-4-fluoro-benzamide
  • Sb 22045
  • Sb 220453
  • N-(6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl)-3-chloro-4-fluorobenzamide
  • N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-4-yl]-3-chloro-4-fluorobenzamide
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 6 products.