CAS 175215-34-6

3-(7-Isopropyl[1,2,4]triazolo[1,5-b]pyridazin-6-yloxy)-2,2-dimethylpropanesulfonamide

Description:

3-(7-Isopropyl[1,2,4]triazolo[1,5-b]pyridazin-6-yloxy)-2,2-dimethylpropanesulfonamide is a chemical compound characterized by its complex structure, which includes a triazole and pyridazine moiety. This compound features a sulfonamide functional group, which is known for its biological activity, particularly in medicinal chemistry. The presence of the isopropyl group contributes to its lipophilicity, potentially influencing its pharmacokinetic properties. The triazole ring is often associated with various biological activities, including antimicrobial and antifungal properties. Additionally, the compound's sulfonamide group may enhance its solubility in polar solvents, making it suitable for various applications in pharmaceuticals. Its specific interactions and mechanisms of action would depend on its conformation and the presence of functional groups that can engage in hydrogen bonding or other intermolecular interactions. Overall, this compound exemplifies the intricate design often found in drug development, where structural features are tailored to optimize efficacy and safety profiles.

Formula: C₁₃H₂₁N₅O₃S

Synonyms:

• TAK-661
• 1-Propanesulfonamide, 2,2-dimethyl-3-[[7-(1-methylethyl)[1,2,4]triazolo[1,5-b]pyridazin-6-yl]oxy]-

TAK-661

CAS: 175215-34-6

TAK-661 is an inhibitor of eosinophil chemotaxis (eosinophil chemotaxis) that significantly alleviates late-phase bronchoconstriction while inhibiting the proliferation of eosinophils in bronchoalveolar lavage (BAL) and their infiltration into the airway walls.

Formula: C₁₃H₂₁N₅O₃S

Color and Shape: Solid

Molecular weight: 327.40

Ref: TM-T201069