CAS 17528-90-4

(16beta,17beta)-16,17-dihydroxyandrost-4-en-3-one

Description:

The chemical substance known as (16beta,17beta)-16,17-dihydroxyandrost-4-en-3-one, with the CAS number 17528-90-4, is a steroid compound that belongs to the class of androgens. It features a steroid backbone characterized by a four-ring structure typical of steroids, with specific hydroxyl (-OH) groups at the 16 and 17 positions, which are crucial for its biological activity. This compound is a derivative of testosterone and is involved in various physiological processes, including the regulation of male characteristics and reproductive functions. The presence of hydroxyl groups enhances its solubility and reactivity, influencing its interaction with biological receptors. It is often studied in the context of hormonal therapies and anabolic steroid research. Additionally, its structural modifications can affect its potency and efficacy as a therapeutic agent. As with many steroid compounds, it is important to handle this substance with care due to its potential biological effects and regulatory status in various jurisdictions.

Formula: C₁₉H₂₈O₃

InChI: InChI=1/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14+,15+,16+,17+,18+,19+/m1/s1

Synonyms:

• Androst-4-En-3-One, 16,17-Dihydroxy-, (16Beta,17Beta)-

16beta-Hydroxytestosterone

Controlled Product

CAS: 17528-90-4

Formula: C₁₉H₂₈O₃

Color and Shape: Neat

Molecular weight: 304.424

Ref: TR-H954100

16β-Hydroxytestosterone

Controlled Product

CAS: 17528-90-4

16β-Hydroxytestosterone is a synthetic androgen that is developed as a male contraceptive. The drug was reconstituted to be injected into the rat liver microsomes, which are the primary site of metabolism. 16β-Hydroxytestosterone inhibits the activities of NADPH-cytochrome P450 reductase (CPR) and cytochrome P450 enzymes, including CYP2D6, CYP3A4, CYP2C19, and CYP1A2. It also inhibits the activity of monoclonal antibodies that bind to CPR. In this study, 16β-hydroxytestosterone has been shown to inhibit the activity of p450 isozymes in Sprague-Dawley rats without affecting other enzyme activities. 16β-Hydroxytestosterone can be used for the treatment of prostate cancer or for contraception in males. This drug should not be used with nitrates or other drugs containing nitric oxide because

Formula: C₁₉H₂₈O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 304.4 g/mol

Ref: 3D-SAA52890