CAS 1754-58-1

Diamidafos

Description:

Diamidafos, with the CAS number 1754-58-1, is an organophosphorus compound primarily used as an insecticide and acaricide in agricultural applications. It is characterized by its ability to inhibit acetylcholinesterase, an enzyme crucial for the proper functioning of the nervous system in insects, leading to paralysis and death. Diamidafos is typically a colorless to pale yellow liquid with a distinctive odor, and it is soluble in organic solvents but has limited solubility in water. The compound is known for its effectiveness against a variety of pests, including aphids and mites, making it valuable in crop protection. However, like many organophosphates, it poses potential risks to non-target organisms, including humans, if not handled properly. Safety measures are essential when using this chemical, as it can be toxic through inhalation, skin contact, or ingestion. Regulatory agencies often monitor its use to mitigate environmental impact and ensure safe application practices in agricultural settings.

Formula: C₈H₁₃N₂O₂P

InChI: InChI=1S/C8H13N2O2P/c1-9-13(11,10-2)12-8-6-4-3-5-7-8/h3-7H,1-2H3,(H2,9,10,11)

InChI key: InChIKey=ZKIBFASDNPOJFP-UHFFFAOYSA-N

SMILES: P(OC1=CC=CC=C1)(NC)(NC)=O

Synonyms:

• Diamidafos [ANSI:ISO]
• Diamidfos
• Nellite
• Ai3-27222
• Brn 0880587
• Caswell No. 654B
• Diamidafos
• Diamidafos [ANSI]
• Diamidaphos
• Diamidofos
• Dowco 169
• EPA Pesticide Chemical Code 102101
• Hsdb 1751
• O-Phenyl-N,N'-dimethyl phosphorodiamidate
• Phosphorodiamidic acid, N,N'-dimethyl-, phenyl ester
• 3-06-00-00662 (Beilstein Handbook Reference)

Diamidafos

Controlled Product

CAS: 1754-58-1

Applications Diamidafos is a useful building block and a pesticide whose residues are sometimes found in fruits and vegetables.
References Kaewsuya, P.; et al.: J. Agric. Food. Chem., 61, 2299 (2013).

Formula: C₈H₁₃N₂O₂P

Color and Shape: Neat

Molecular weight: 200.175

Ref: TR-D120100

Diamidafos

CAS: 1754-58-1

Diamidafos is a potent anticancer drug that has been used in Chinese traditional medicine to treat tumors. It acts as a protein kinase inhibitor, preventing the phosphorylation of proteins involved in cell growth and survival. Diamidafos is an analog of staurosporine, one of the first protein kinase inhibitors discovered. It has been shown to induce apoptosis in cancer cells by inhibiting the activity of various kinases. Diamidafos has also been found to inhibit the growth of human cancer cells and reduce tumor size in animal models. In addition, it can be administered orally and is excreted primarily through urine. To improve its efficacy, diamidafos can be combined with chitosan, a natural polymer that enhances drug delivery and bioavailability.

Formula: C₈H₁₃N₂O₂P

Purity: Min. 95%

Molecular weight: 200.17 g/mol

Ref: 3D-BAA75458