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CAS 17543-17-8

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Z-Asp(OtBu)-ONp

Description:
Z-Asp(OtBu)-ONp, also known as Z-Aspartic acid tert-butyl ester p-nitrophenyl ester, is a chemical compound commonly used in peptide synthesis and biochemistry. It features a protected aspartic acid moiety, where the carboxylic acid group is esterified with a tert-butyl group, providing stability and solubility in organic solvents. The "Z" (benzyloxycarbonyl) group serves as a protective group for the amino function, allowing for selective reactions without interfering with the amine. The p-nitrophenyl (ONp) group is a leaving group that can be activated under specific conditions, facilitating the coupling of amino acids in peptide synthesis. This compound is typically utilized in the formation of peptide bonds, making it valuable in the development of pharmaceuticals and biologically active peptides. Its stability, ease of handling, and reactivity under controlled conditions make it a useful reagent in organic synthesis and medicinal chemistry. As with all chemical substances, proper safety protocols should be followed when handling Z-Asp(OtBu)-ONp.
Formula:C22H24N2O8
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