CAS 175448-32-5

Benzamide, 2-hydroxy-N-(6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo(4.1.0 )hept-3-en-3-yl)-, (1S)-

Description:

Benzamide, 2-hydroxy-N-(6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-, with CAS number 175448-32-5, is a complex organic compound characterized by its bicyclic structure and functional groups. It features a benzamide moiety, which is known for its amide functional group attached to a benzene ring, contributing to its potential as a pharmacophore in medicinal chemistry. The presence of hydroxymethyl and hydroxy groups indicates that it may exhibit hydrogen bonding capabilities, influencing its solubility and reactivity. The bicyclic framework suggests potential rigidity, which can affect the compound's conformational properties and interactions with biological targets. This compound may also possess unique chemical reactivity due to the dioxo and oxabicyclo components, making it of interest in synthetic organic chemistry and drug development. Overall, its structural complexity and functional diversity suggest potential applications in various fields, including pharmaceuticals and materials science.

Formula: C₁₄H₁₁NO₆

InChI: InChI=1/C14H11NO6/c16-6-14-10(18)5-8(11(19)12(14)21-14)15-13(20)7-3-1-2-4-9(7)17/h1-5,12,16-17H,6H2,(H,15,20)/t12-,14+/m1/s1

Synonyms:

• Epoxyquinomicin B
• Benzamide, 2-hydroxy-N-(6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)-, (1S)-
• Benzamide, 2-hydroxy-N-[(1S,6R)-6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-
• Benzamide, 2-hydroxy-N-(6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo(4.1.0 )hept-3-en-3-yl)-, (1S)-
• (1S)-2-Hydroxy-N-(6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo(4.1.0)hept-3-en-3-yl)benzamide
• 2-hydroxy-N-[(1S,6R)-6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]benzamide

Epoxyquinomicin B

CAS: 175448-32-5

Epoxyquinomicin B is an antibiotic isolated from Amycolatopsissp. It exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida, and Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of 6.25-12.5 µg/mL. It also shows cytotoxicity in cancer cells L1210, with an IC50 of 16.3 µg/mL. Additionally, Epoxyquinomicin B demonstrates anti-inflammatory effects on collagen-induced arthritis.

Formula: C₁₄H₁₁NO₆

Color and Shape: Solid

Molecular weight: 289.24

Ref: TM-TN10027