CAS 175481-36-4
:Lacosamide
Description:
Lacosamide is a pharmaceutical compound primarily used as an anticonvulsant in the treatment of epilepsy. It is classified as a functionalized amino acid and is known for its ability to stabilize neuronal membranes and inhibit repetitive neuronal firing. The chemical formula of lacosamide is C15H18N2O2, and it features a unique structure that includes a phenyl ring and an amide functional group. Lacosamide acts by enhancing the inactivation of voltage-gated sodium channels, which helps to reduce the excitability of neurons. It is typically administered orally or intravenously and is well-absorbed in the gastrointestinal tract. The substance has a favorable pharmacokinetic profile, with a relatively long half-life, allowing for once or twice daily dosing. Common side effects may include dizziness, nausea, and headache, but it is generally well-tolerated. Lacosamide is also being investigated for potential use in other neurological disorders, reflecting its broad therapeutic potential beyond epilepsy.
Formula:C13H18N2O3
InChI:InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
InChI key:InChIKey=VPPJLAIAVCUEMN-GFCCVEGCSA-N
SMILES:C(NC([C@H](NC(C)=O)COC)=O)C1=CC=CC=C1
Synonyms:- (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide
- (2R)-2-Acetamido-N-benzyl-3-methoxypropanamide
- (2R)-2-acetamido-N-benzyl-3-methoxy-propanamide
- (R)-2-Acetamido-N-benzyl-3-methoxypropionamide
- (R)-2-acetamido-N-benzyl-3-methoxypropanamide
- Add 243037
- Erlosamide
- Harkoseride
- Lacosamide UCB
- Lacoset
- Lacoset 50
- N~2~-acetyl-N-benzyl-O-methyl-D-serinamide
- Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-
- Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (R)-
- Spm 927
- See more synonyms
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Found 13 products.
Lacosamide
CAS:Formula:C13H18N2O3Purity:(HPLC) ≥ 98.0%Color and Shape:White to off-white powderMolecular weight:250.29Lacosamide-d3 (Acetyl-d3)
CAS:Formula:C13H15D3N2O3Color and Shape:White To Off-White SolidMolecular weight:253.32Lacosamide
CAS:Controlled Product<p>Applications Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),<br></p>Formula:C13H18N2O3Color and Shape:Off-WhiteMolecular weight:250.29Lacosamide - Bio-X ™
CAS:Controlled Product<p>Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.</p>Formula:C13H18N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:250.29 g/molLacosamide
CAS:Controlled Product<p>Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.</p>Formula:C13H18N2O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:250.29 g/molLacosamide-d6
CAS:Controlled Product<p>Applications Labelled Lacosamide (L098500). Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.<br>References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),<br></p>Formula:C13D6H12N2O3Color and Shape:NeatMolecular weight:256.331Lacosamide CV ((+)-(R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide)
CAS:Controlled ProductAromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereofFormula:C13H18N2O3Color and Shape:White Light Yellow PowderMolecular weight:250.13174
