CAS 175481-36-4

Lacosamide

Description:

Lacosamide is a pharmaceutical compound primarily used as an anticonvulsant in the treatment of epilepsy. It is classified as a functionalized amino acid and is known for its ability to stabilize neuronal membranes and inhibit repetitive neuronal firing. The chemical formula of lacosamide is C15H18N2O2, and it features a unique structure that includes a phenyl ring and an amide functional group. Lacosamide acts by enhancing the inactivation of voltage-gated sodium channels, which helps to reduce the excitability of neurons. It is typically administered orally or intravenously and is well-absorbed in the gastrointestinal tract. The substance has a favorable pharmacokinetic profile, with a relatively long half-life, allowing for once or twice daily dosing. Common side effects may include dizziness, nausea, and headache, but it is generally well-tolerated. Lacosamide is also being investigated for potential use in other neurological disorders, reflecting its broad therapeutic potential beyond epilepsy.

Formula: C₁₃H₁₈N₂O₃

InChI: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1

InChI key: InChIKey=VPPJLAIAVCUEMN-GFCCVEGCSA-N

SMILES: C(NC([C@H](NC(C)=O)COC)=O)C1=CC=CC=C1

Synonyms:

• (2R)-2-(Acetylamino)-3-methoxy-N-(phenylmethyl)propanamide
• (2R)-2-Acetamido-N-benzyl-3-methoxypropanamide
• (2R)-2-acetamido-N-benzyl-3-methoxy-propanamide
• (R)-2-Acetamido-N-benzyl-3-methoxypropionamide
• (R)-2-acetamido-N-benzyl-3-methoxypropanamide
• Add 243037
• Erlosamide
• Harkoseride
• Lacosamide UCB
• Lacoset
• Lacoset 50
• N~2~-acetyl-N-benzyl-O-methyl-D-serinamide
• Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-
• Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (R)-
• Spm 927

Lacosamide

CAS: 175481-36-4

Color and Shape: Neat

Ref: 61-FOR3640.00

Lacosamide 1.0 mg/ml in Acetonitrile

Controlled Product

CAS: 175481-36-4

Color and Shape: Single Solution

Ref: 61-AMP3640.00-11

LACOSAMIDE FOR SYSTEM SUITABILITY CRS

CAS: 175481-36-4

LACOSAMIDE FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001973

LACOSAMIDE CRS

CAS: 175481-36-4

LACOSAMIDE CRS

Ref: 41-Y0001982

Lacosamide

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 250.29

Ref: 7W-GP3690

Lacosamide

CAS: 175481-36-4

Formula: C₁₃H₁₈N₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 250.30

Ref: 4Z-L-281

Lacosamide-d3 (Acetyl-d3)

CAS: 175481-36-4

Formula: C₁₃H₁₅D₃N₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 253.32

Ref: 4Z-L-283

Lacosamide

Controlled Product

CAS: 175481-36-4

Color and Shape: Neat

Ref: 86-MM3640.00

Lacosamide

Controlled Product

CAS: 175481-36-4

Applications Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),

Formula: C₁₃H₁₈N₂O₃

Color and Shape: Off-White

Molecular weight: 250.29

Ref: TR-L098500

Lacosamide - Bio-X ™

Controlled Product

CAS: 175481-36-4

Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.

Formula: C₁₃H₁₈N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 250.29 g/mol

Ref: 3D-BL164605

Lacosamide

Controlled Product

CAS: 175481-36-4

Lacosamide is a drug that is used for the treatment of epilepsy. It has been shown to inhibit neuronal death in vitro and in animal models, and has been extensively studied for its potential benefits in the treatment of bowel disease. The mechanism of action for lacosamide involves inhibition of the transport of neurotransmitters from the synaptic cleft by binding to the neuronal sodium channels and increasing their recovery rate. Lacosamide has also been found to affect energy metabolism by inhibiting the activity of mitochondrial enzymes such as matrix effect and complex I/III.

Formula: C₁₃H₁₈N₂O₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 250.29 g/mol

Ref: 3D-FL24825

Lacosamide-d6

Controlled Product

CAS: 175481-36-4

Applications Labelled Lacosamide (L098500). Lacosamide is a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997), Barton, M., et al.: Epilepsy Res., 47, 217 (2001), Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006), Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007),

Formula: C₁₃D₆H₁₂N₂O₃

Color and Shape: Neat

Molecular weight: 256.331

Ref: TR-L098503

Lacosamide CV ((+)-(R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide)

Controlled Product

CAS: 175481-36-4

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Formula: C₁₃H₁₈N₂O₃

Color and Shape: White Light Yellow Powder

Molecular weight: 250.13174

Ref: 45-1357103