Okadaic acid ammonium salt is a derivative of okadaic acid, a polyether compound originally isolated from marine organisms, particularly certain species of dinoflagellates. This compound is known for its potent inhibitory effects on protein phosphatases, specifically PP1 and PP2A, which play crucial roles in cellular signaling and regulation. As a result, okadaic acid and its derivatives are often studied for their implications in cancer research and cell biology. The ammonium salt form enhances its solubility in water, making it more accessible for various biochemical applications. In terms of physical properties, okadaic acid ammonium salt typically appears as a white to off-white solid. It is important to handle this compound with care, as it can be toxic and has been associated with marine biotoxins that cause gastrointestinal disturbances in humans. Additionally, its use in research is subject to regulatory guidelines due to its biological activity and potential health risks.

Okadaic acid ammonium salt

175522-42-6: Okadaic acid ammonium salt is a derivative of okadaic acid, a polyether compound originally isolated from marine organisms, particularly certain species of dinoflagellates. This compound is known for its potent inhibitory effects on protein phosphatases, specifically PP1 and PP2A, which play crucial roles in cellular signaling and regulation. As a result, okadaic acid and its derivatives are often studied for their implications in cancer research and cell biology. The ammonium salt form enhances its solubility in water, making it more accessible for various biochemical applications. In terms of physical properties, okadaic acid ammonium salt typically appears as a white to off-white solid. It is important to handle this compound with care, as it can be toxic and has been associated with marine biotoxins that cause gastrointestinal disturbances in humans. Additionally, its use in research is subject to regulatory guidelines due to its biological activity and potential health risks.

<p>Marine toxin Okadaic acid ammonium salt inhibits protein phosphatases, promotes tumors, and induces tau phosphorylation. PP2A most affected (IC50=0.1-0.3nM).</p>

CAS 175522-42-6

Okadaic acid ammonium salt

Okadaic acid ammonium salt

Ref: TM-T39183