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CAS 17555-51-0

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25-deacetoxy-25-hydroxyrifamycin S

Description:
25-Deacetoxy-25-hydroxyrifamycin S is a derivative of rifamycin, a class of antibiotics known for their efficacy against bacterial infections, particularly tuberculosis. This compound features a complex macrocyclic structure that includes a naphthalenic core, which is characteristic of rifamycins. The presence of hydroxyl and acetoxy functional groups contributes to its chemical reactivity and biological activity. It exhibits antibacterial properties by inhibiting bacterial RNA synthesis, specifically targeting bacterial RNA polymerase. The compound is typically characterized by its solubility in organic solvents and limited solubility in water, which influences its pharmacokinetics and bioavailability. Additionally, it may undergo various metabolic transformations in biological systems, affecting its therapeutic efficacy and safety profile. As with other rifamycins, the potential for resistance development in bacteria is a significant consideration in its clinical use. Overall, 25-deacetoxy-25-hydroxyrifamycin S represents a valuable compound in the ongoing fight against resistant bacterial strains.
Formula:C35H43NO11
InChI:InChI=1/C35H43NO11/c1-15-10-9-11-16(2)34(44)36-21-14-22(37)24-25(31(21)42)30(41)20(6)32-26(24)33(43)35(7,47-32)46-13-12-23(45-8)17(3)28(39)19(5)29(40)18(4)27(15)38/h9-15,17-19,23,27-29,38-41H,1-8H3,(H,36,44)/b10-9+,13-12+,16-11+
Synonyms:
  • 25-Deacetoxy-25-epi-hydroxyrifamycin S
  • 25-Dehr
  • Rifamycin, 25-O-deacetyl-1,4-dideoxy-1,4-dihydro-1,4-dioxo-
  • (14E,24E)-5,17,19,21-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-2,7-(epoxypentadeca[1,11,13]trienoimino)naphtho[2,1-b]furan-1,6,9,11(2H)-tetrone
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Found 3 products.
  • Desacetyl Rifamycin S
    TLC
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    Desacetyl Rifamycin S

    CAS:
    Formula:C35H43NO11
    Color and Shape:Yellow Brown Solid
    Molecular weight:653.73

    Ref: 4Z-R-077006

    5mg
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    10mg
    1,456.00€
    25mg
    2,670.00€
    50mg
    4,368.00€
    100mg
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  • Desacetyl Rifamycin S
    TRC
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    Desacetyl Rifamycin S

    Controlled Product
    CAS:
    Formula:C35H43NO11
    Color and Shape:Neat
    Molecular weight:653.716

    Ref: TR-D399730

    100mg
    1,530.00€
  • 25-Deacetoxy-25-hydroxyrifamycin S
    Standalix
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    25-Deacetoxy-25-hydroxyrifamycin S

    CAS:
    Formula:C35H43NO11
    Molecular weight:653.7

    Ref: ST-EA-CP-R12006

    10mg
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    25mg
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    50mg
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    100mg
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