CAS 175591-09-0

Tapentadol Hydrochloride

Description:

Tapentadol hydrochloride is a synthetic opioid analgesic primarily used for the management of moderate to severe pain. It functions through dual mechanisms: it acts as a mu-opioid receptor agonist and inhibits the reuptake of norepinephrine, which contributes to its analgesic effects. The chemical formula for tapentadol hydrochloride is C14H17NO2·HCl, and it has a molecular weight of approximately 273.75 g/mol. This compound is typically presented as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Tapentadol is known for its relatively lower risk of gastrointestinal side effects compared to traditional opioids, which can enhance patient compliance. However, like other opioids, it carries the potential for abuse, dependence, and withdrawal symptoms. Its pharmacokinetics include a moderate half-life, allowing for effective pain management with appropriate dosing intervals. Overall, tapentadol hydrochloride represents a valuable option in pain management, particularly for patients who may not tolerate other opioid medications.

Formula: C₁₄H₂₄ClNO

InChI: InChI=1/C14H23NO/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12/h6-9,11,14,16H,5,10H2,1-4H3/t11-,14+/m0/s1

InChI key: InChIKey=ZELFLGGRLLOERW-YECZQDJWSA-N

SMILES: [C@H]([C@H](CN(C)C)C)(CC)C1=CC(O)=CC=C1.Cl

Synonyms:

• 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol Hydrochloride
• 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol
• Nucynta
• Phenol, 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]-, hydrochloride
• Phenol, 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]-, hydrochloride (1:1)
• Phenol, 3-[3-(dimethylamino)-1-ethyl-2-methylpropyl]-, hydrochloride, [R-(R*,R*)]-
• Tapal
• Tapenta
• Tapentadol HCl
• Tydol
• Zyntap
• Tapentadol hydrochloride
• 3-((2R,3R)-1-(diMethylaMino)-2-Methylpentan-3-yl)phenol hydrochloride
• Tapentadol hydrochloride solution
• Tapentadol hydrochloride(Y0002120)
• Tapentadol HydrochlorideQ: What is
• Phenol, 3-[(1R,2R)-3-(diMethylaMino)-1-ethyl-2-Methylpropyl]-, (HCl salt)
• Tapentadol Hydrochloride Q: What is the storage condition of
• 3-[(1R,2R)-3-(DiMethylaMino)-1-ethyl-2-Methylpro
• Tapentadol (hydrochloride) (CRM)
• Tapentadol Hydrochloride Q: What are the applications of
• benzyl hydrogen (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate
• Tapentediol
• Tapentadol Hydrochloride (1.0 mg/mL in Methanol)

Tapentadol.HCl, 1mg/ml in Methanol (as free base)

Controlled Product

CAS: 175591-09-0

Color and Shape: Single Solution

Ref: LP-TAP-1665-HC-1LM

Tapentadol.HCl

Controlled Product

CAS: 175591-09-0

Color and Shape: Light Brown

Ref: LP-TAP-1665-HC-10

Tapentadol Hydrochloride

Controlled Product

CAS: 175591-09-0

Applications Centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy in preclinical and clinical models of pain relief.
References Boxenbaum, H., et al.: J. Pharm. Sci., 2, 47 (1999),Boase, S., et al.: Br. J. Clin. Pharmacol., 54, 493 (2002),Armstrong, S., et al.: Psychosomatics, 44, 515 (2003), Bjornsson, T., et al.: Drug Metab. Dispos., 31, 815 ( 2003),

Formula: C₁₄H₂₃NO·ClH

Color and Shape: Light Brown

Molecular weight: 257.80

Ref: TR-T007200

Tapentadol hydrochloride

Controlled Product

CAS: 175591-09-0

Tapentadol hydrochloride is a potent analgesic that belongs to the class of centrally acting opioids. It works by binding to mu-opioid receptors in the brain and spinal cord, thereby reducing pain signals transmitted to the brain. Tapentadol hydrochloride has been shown to be effective in treating moderate-to-severe pain associated with conditions such as osteoarthritis, neuropathic pain, and cancer-related pain. However, it should be used with caution in patients taking other drugs that affect bleeding, such as warfarin or dabigatran. Tapentadol hydrochloride has also been shown to have some bronchodilatory effects similar to formoterol and sertindole but without any significant impact on asthma or strain. The drug is available in various forms such as tablets, capsules, alginate pellets, and solutions for injection or oral use.

Formula: C₁₄H₂₃NO•HCl

Purity: Min. 98%

Molecular weight: 257.8 g/mol

Ref: 3D-BT182778

TAPENTADOL HYDROCHLORIDE CRS - * NARC

Controlled Product

CAS: 175591-09-0

TAPENTADOL HYDROCHLORIDE CRS - * NARC

Ref: 41-Y0002120

Tapentadol Hydrochloride (1 mg/mL in Methanol)

Controlled Product

CAS: 175591-09-0

Formula: C₁₄H₂₃NO·ClH

Color and Shape: Single Solution

Molecular weight: 257.80

Ref: TR-KIT0170