CAS 175591-09-0: Tapentadol Hydrochloride

Description: Tapentadol hydrochloride is a synthetic opioid analgesic primarily used for the management of moderate to severe pain. It functions through dual mechanisms: it acts as a mu-opioid receptor agonist and inhibits the reuptake of norepinephrine, which contributes to its analgesic effects. The chemical formula for tapentadol hydrochloride is C14H17NO2·HCl, and it has a molecular weight of approximately 273.75 g/mol. This compound is typically presented as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Tapentadol is known for its relatively lower risk of gastrointestinal side effects compared to traditional opioids, which can enhance patient compliance. However, like other opioids, it carries the potential for abuse, dependence, and withdrawal symptoms. Its pharmacokinetics include a moderate half-life, allowing for effective pain management with appropriate dosing intervals. Overall, tapentadol hydrochloride represents a valuable option in pain management, particularly for patients who may not tolerate other opioid medications.

Formula: C₁₄H₂₃NO

InChI: InChI=1S/C14H23NO.ClH/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12;/h6-9,11,14,16H,5,10H2,1-4H3;1H/t11-,14+;/m0./s1

InChI key: InChIKey=ZELFLGGRLLOERW-YECZQDJWSA-N

SMILES: Cl.OC1=CC=CC(=C1)C(CC)C(C)CN(C)C

Synonyms:

• 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol Hydrochloride
• 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]phenol
• Nucynta
• Phenol, 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]-, hydrochloride
• Phenol, 3-[(1R,2R)-3-(dimethylamino)-1-ethyl-2-methylpropyl]-, hydrochloride (1:1)
• Phenol, 3-[3-(dimethylamino)-1-ethyl-2-methylpropyl]-, hydrochloride, [R-(R*,R*)]-
• Tapal
• Tapenta
• Tapentadol HCl
• Tydol
• Zyntap

Tapentadol Hydrochloride

CAS: 175591-09-0

Applications Centrally acting oral analgesic with a dual mode of action that has demonstrated efficacy …

• Formula: C₁₄H₂₃NO·ClH
• Color and Shape: Light Brown
• Molecular weight: 257.80

Tapentadol hydrochloride

CAS: 175591-09-0

Tapentadol hydrochloride is a potent analgesic that belongs to the class of centrally acting opioids. …

• Formula: C₁₄H₂₃NO•HCl
• Purity: Min. 98%
• Molecular weight: 257.8 g/mol

Tapentadol hydrochloride CRS - * narc

CAS: 175591-09-0

Tapentadol Hydrochloride (1.0 mg/mL in Methanol)

CAS: 175591-09-0

• Formula: C₁₄H₂₃NO·ClH
• Color and Shape: Single Solution
• Molecular weight: 257.80