CAS 175676-65-0

2-(Trifluormethoxy)phenylboronic acid

Description:

2-(Trifluoromethoxy)phenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring that is further substituted with a trifluoromethoxy group. This compound typically exhibits properties such as high reactivity due to the boronic acid moiety, which can participate in various chemical reactions, including Suzuki coupling and other cross-coupling reactions. The trifluoromethoxy group enhances the compound's lipophilicity and can influence its electronic properties, making it a valuable building block in organic synthesis and medicinal chemistry. Additionally, the presence of fluorine atoms often imparts unique characteristics, such as increased stability and altered solubility in organic solvents. The compound is generally used in the development of pharmaceuticals and agrochemicals, as well as in materials science for creating functionalized polymers. Safety data should be consulted for handling and storage, as organoboron compounds can pose specific hazards.

Formula: C₇H₆BF₃O₃

InChI: InChI=1/C7H6BF3O3/c9-7(10,11)14-6-4-2-1-3-5(6)8(12)13/h1-4,12-13H

SMILES: c1ccc(c(c1)B(O)O)OC(F)(F)F

Synonyms:

• 2-(Trifluoromethoxy)phenylboronicacid
• 2-(Trifluoromethoxy)phenylboronic acid

Boronic acid, B-[2-(trifluoromethoxy)phenyl]-

CAS: 175676-65-0

Formula: C₇H₆BF₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 205.9269

Ref: IN-DA002143

2-Trifluoromethoxyphenylboronic acid

CAS: 175676-65-0

Formula: C₇H₆BF₃O₃

Molecular weight: 205.93

Ref: 7W-GK0364

2-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)

CAS: 175676-65-0

Formula: C₇H₆BF₃O₃

Purity: 97.0 to 110.0 %

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 205.93

Ref: 3B-T2413

2-(Trifluoromethoxy)benzeneboronic acid

CAS: 175676-65-0

2-(Trifluoromethoxy)benzeneboronic acid

Formula: C₇H₆BF₃O₃

Purity: ≥95%

Color and Shape: white to off-white crystalline solid

Molecular weight: 205.93g/mol

Ref: 54-PC4560

2-(Trifluoromethoxy)benzeneboronic acid

CAS: 175676-65-0

Formula: C₇H₆BF₃O₃

Purity: 98%

Color and Shape: Off-white powder

Molecular weight: 205.93

Ref: 10-F013043

2-(Trifluoromethoxy)phenylboronic acid

CAS: 175676-65-0

2-(Trifluoromethoxy)phenylboronic acid (2-TFB) is a boronic acid that is used in cross-coupling reactions. It has been shown to be an effective inhibitor of the Vismodegib pathway, which may offer therapeutic benefits for cancer patients. 2-TFB has also been shown to inhibit the activity of other pathways involved in cancer development, such as the benzamide and suzuki pathways. 2-TFB is metabolized through filtration, which can lead to significant pharmacokinetic properties. This compound can be recycled and reused in cross-coupling reactions, which reduces waste production and costs.

Formula: C₇H₆BF₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 205.93 g/mol

Ref: 3D-FT37712