CAS 17598-65-1

Deslanoside

Description:

Deslanoside is a cardiac glycoside, primarily derived from the plant Digitalis lanata, and is used in the treatment of heart conditions, particularly heart failure and atrial fibrillation. It functions by inhibiting the sodium-potassium ATPase pump, leading to an increase in intracellular sodium and calcium concentrations, which enhances cardiac contractility. Deslanoside is characterized by its ability to improve the efficiency of the heart's pumping action while also exerting a negative chronotropic effect, which slows down heart rate. The compound is typically administered in a controlled manner due to its narrow therapeutic index, meaning that the difference between an effective dose and a toxic dose is small. Side effects can include gastrointestinal disturbances, visual changes, and arrhythmias, necessitating careful monitoring of serum levels. Deslanoside is often used in conjunction with other medications to optimize heart function and manage symptoms effectively. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion that can be influenced by various factors, including patient-specific characteristics and concurrent medications.

Formula: C₄₇H₇₄O₁₉

InChI: InChI=1/C47H74O19/c1-20-41(64-36-16-30(50)42(21(2)60-36)65-37-17-31(51)43(22(3)61-37)66-44-40(56)39(55)38(54)32(18-48)63-44)29(49)15-35(59-20)62-25-8-10-45(4)24(13-25)6-7-27-28(45)14-33(52)46(5)26(9-11-47(27,46)57)23-12-34(53)58-19-23/h12,20-22,24-33,35-44,48-52,54-57H,6-11,13-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,33-,35+,36+,37+,38-,39+,40-,41-,42-,43-,44+,45+,46+,47+/m1/s1

InChI key: InChIKey=OBATZBGFDSVCJD-LALPQLPRSA-N

SMILES: O[C@@]12[C@@](C)([C@H](CC1)C3=CC(=O)OC3)[C@H](O)C[C@]4([C@]2(CC[C@]5([C@]4(C)CC[C@H](O[C@H]6C[C@H](O)[C@H](O[C@H]7C[C@H](O)[C@H](O[C@H]8C[C@H](O)[C@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@@H](C)O8)[C@@H](C)O7)[C@@H](C)O6)C5)[H])[H])[H]

Synonyms:

• (3beta,5beta,12beta)-3-{[beta-D-glucopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
• (3β,5β,12β)-3-[(O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• Card-20(22)-enolide, 3-[(O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
• Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)-
• Cedilanid D
• Cedilanidd
• De-O-acetyllanatoside C
• Deacetyl-Lanatoside
• Deacetylanatoside C
• Deacetyllanatoside C
• Desace
• Desacetyllanatoside C
• Desacetyllanatosidec
• Desaci
• Descetyldigilanidec
• Deslanatoside
• Deslanatoside C
• Deslanosid
• Deslanoside C
• Deslanosido
• Deslanosidum
• Lanatoside C, deacetyl-
• Purpurea glycoside C
• Deslanoside
• (3β,5β,12β)-3-[(O-β-D-Glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxycard-20(22)-enolide
• Desacetyl-Lanatosid C
• sediranido
• Lanatoside C, deacetyl-(6CI, 7CI, 8CI)

DESLANOSIDE CRS

CAS: 17598-65-1

DESLANOSIDE CRS

Ref: 41-D0600000

Deslanoside

CAS: 17598-65-1

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₄₇H₇₄O₁₉

Color and Shape: Powder

Molecular weight: 942.48243

Ref: 45-1173009

Deslanoside

CAS: 17598-65-1

Deslanoside

Purity: ≥98%

Molecular weight: 943.08g/mol

Ref: 54-BUP20803

Deslanoside

CAS: 17598-65-1

Deslanoside is a fast-acting cardiac glycoside for heart failure and arrhythmias, blocking Na-K-ATPase to boost sodium and calcium.

Formula: C₄₇H₇₄O₁₉

Purity: 99.39% - 99.89%

Color and Shape: Solid

Molecular weight: 943.08

Ref: TM-T8183

Deslanoside RS

CAS: 17598-65-1

Color and Shape: Colorless Or White

Ref: 2K-1085000021

Desacetyllanatoside C

Controlled Product

CAS: 17598-65-1

Applications Desacetyllanatoside C is a derivative of Lanatoside C (L173800), glycosides isolated from various species of Digitalis. Cardiotonic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Novotny, J., et al.: J. Biol. Chem., 258, 14433 (1983), Farr, C., et al.: J. Med. Chem., 45, 3257 (2002), Van Dongen, M., et al.: Drug Discov. Today, 7, 471 (2002),

Formula: C₄₇H₇₄O₁₉

Color and Shape: Neat

Molecular weight: 943.08

Ref: TR-D288320

Deslanoside

CAS: 17598-65-1

Deslanoside is a cardiac glycoside, which is derived from the leaves of the Digitalis lanata plant. As a member of the cardiac glycoside family, it functions by inhibiting the Na⁺/K⁺-ATPase pump. This inhibition results in an increase in intracellular sodium levels, which subsequently leads to a rise in intracellular calcium concentrations via the sodium-calcium exchange mechanism. The elevated calcium levels enhance the force of myocardial contraction, making it a potent inotropic agent.

Formula: C₄₇H₇₄O₁₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 943.08 g/mol

Ref: 3D-MD65946