CAS 176-80-7

1-Azaspiro[4.5]decane

Description:

1-Azaspiro[4.5]decane, with the CAS number 176-80-7, is a bicyclic organic compound characterized by its unique spiro structure, which consists of a nitrogen atom integrated into a bicyclic framework. This compound features a spiro junction between a five-membered and a six-membered ring, contributing to its distinctive three-dimensional shape. It is a colorless to pale yellow liquid at room temperature and has a relatively low volatility. The presence of the nitrogen atom in its structure imparts basic properties, allowing it to participate in various chemical reactions, including nucleophilic substitutions. 1-Azaspiro[4.5]decane is of interest in medicinal chemistry and materials science due to its potential applications in drug design and as a building block for more complex molecules. Its unique structural features may influence its biological activity and interactions with other compounds. As with many nitrogen-containing heterocycles, it may exhibit interesting pharmacological properties, making it a subject of research in various fields.

Formula: C₉H₁₇N

InChI: InChI=1S/C9H17N/c1-2-5-9(6-3-1)7-4-8-10-9/h10H,1-8H2

InChI key: InChIKey=LGKNCSVHCNCJQG-UHFFFAOYSA-N

SMILES: C12(CCCCC1)CCCN2

Synonyms:

• 2,2-Pentamethylenepyrrolidine
• Brn 0103872
• Nsc 19984
• Pyrrolidine, 2,2-(1,5-pentanediyl)-
• 5-20-04-00400 (Beilstein Handbook Reference)
• 1-Azaspiro[4.5]decane
• 1-Azaspiro(4.5)decane

1-Azaspiro[4.5]decane

CAS: 176-80-7

Formula: C₉H₁₇N

Molecular weight: 139.2380

Ref: IN-DA0021CZ

1-Azaspiro[4.5]decane

CAS: 176-80-7

Formula: C₉H₁₇N

Purity: 95.0%

Molecular weight: 139.242

Ref: 10-F459990

1-Azaspiro[4.5]decane

CAS: 176-80-7

1-Azaspiro[4.5]decane is a compound that contains an azaspiro[4.5]decane skeleton with a formyloxy group at the 1 position and a hydroxyamine group at the 3 position. It has been shown to be an efficient method for the synthesis of peptidomimetics, which are compounds that have a peptide-like structure but are not peptides in the strict sense. The tricycle of 1-azaspiro[4.5]decane is formed through a hydrochloride salt, which is generated by hydrolysis of 1-azaspiro[4.5]decane with hydrochloric acid and then reduced with lithium aluminium hydride, or through reduction with hydrogen over palladium on charcoal in acetic acid. Hydroxyamination of 1-azaspiro[4.5]decane can be accomplished under basic conditions by treatment with ammonia and ethyl acetate, followed by hydro

Formula: C₉H₁₇N

Purity: Min. 95%

Molecular weight: 139.24 g/mol

Ref: 3D-AAA17680