CAS 176106-81-3

Lewis X Trisaccharide, Methyl Glycoside

Description:

Lewis X trisaccharide, methyl glycoside, is a carbohydrate compound characterized by its structure as a trisaccharide, which consists of three monosaccharide units linked together. This compound is a derivative of the Lewis X antigen, a carbohydrate structure that plays a significant role in cell-cell recognition and adhesion processes, particularly in the context of immune responses and cancer biology. The methyl glycoside form indicates that a methyl group is attached to the anomeric carbon of one of the sugar units, which can influence its solubility and reactivity. Typically, such glycosides are more stable and less reactive than their corresponding free sugars. Lewis X trisaccharide is often studied for its biological significance, including its interactions with selectins and its potential applications in therapeutic and diagnostic fields. The CAS number 176106-81-3 uniquely identifies this specific chemical substance, facilitating its recognition in scientific literature and databases. Overall, this compound exemplifies the complexity and importance of carbohydrate chemistry in biological systems.

Formula: C₂₁H₃₇NO₁₅

InChI: InChI=1/C21H37NO15/c1-6-11(26)13(28)15(30)20(33-6)37-18-10(22-7(2)25)19(32-3)35-9(5-24)17(18)36-21-16(31)14(29)12(27)8(4-23)34-21/h6,8-21,23-24,26-31H,4-5H2,1-3H3,(H,22,25)

SMILES: CC1C(C(C(C(O1)OC1C(C(OC)OC(CO)C1OC1C(C(C(C(CO)O1)O)O)O)N=C(C)O)O)O)O

Synonyms:

• Methyl 2-Acetamido-2-deoxy-3-O-(a-L-fucopyranosyl)-4-O-(b-D- galactopyranosyl)-b-D-glucopyranoside, Gal1-b-4[Fuc1-a-3] GlcNAc1-b-O-Me
• LewisXtrisaccharidemethylglucoside
• Methyl 6-Deoxyhexopyranosyl-(1->3)-[Hexopyranosyl-(1->4)]-2-(Acetylamino)-2-Deoxyhexopyranoside

Lewis X Trisaccharide, Methyl Glycoside

CAS: 176106-81-3

Formula: C₂₁H₃₇NO₁₅

Color and Shape: Solid

Molecular weight: 543.5162

Ref: IN-DA0021G2

Lewis X trisaccharide methyl glucoside

CAS: 176106-81-3

Ref: 7W-GC6685

Lewis X Trisaccharide, Methyl Glycoside

Controlled Product

CAS: 176106-81-3

Applications Lewis X and related compounds bind to the selectins and act as anti-inflammatory agents.
References Lasky, L.A.: Science, 258, 964 (1992), Mulligan, M.S., et al.: Nature, 364, 149 (1993), Mulligan, M.S., et al.: J. Exp. Med., 178, 623 (1993), Travis, J.: Science, 260, 906 (1993)

Formula: C₂₁H₃₇NO₁₅

Color and Shape: Neat

Molecular weight: 543.52

Ref: TR-L395500

Lewis X trisaccharide methyl glycoside

CAS: 176106-81-3

Lewis X is a glycoprotein found on the surface of red blood cells and is composed of a trisaccharide that is covalently attached to the protein. It is expressed in the cells of all individuals, but at different levels depending on their blood group. Lewis X is an antigen for monoclonal antibody, which recognizes it by binding to its sugar residues. The antibody can be used to detect Lewis X-expressing cells in the blood and for cancer diagnosis. Antibodies against Lewis X can also be used to inhibit tumor growth by enhancing natural killer cell activity and killing tumor cells.

Formula: C₂₁H₃₇NO₁₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 543.52 g/mol

Ref: 3D-OL04770