CAS 176219-04-8

Omeprazol-N-Oxide

Description:

Omeprazol-N-Oxide is a chemical compound derived from omeprazole, a widely used proton pump inhibitor that reduces stomach acid production. This compound is characterized by its unique structural modification, which includes the presence of an N-oxide functional group. Omeprazol-N-Oxide typically exhibits properties such as being a white to off-white solid, with moderate solubility in organic solvents and limited solubility in water. Its molecular structure contributes to its pharmacological activity, influencing its interaction with biological systems. The compound is primarily studied for its potential effects on gastric acid secretion and its role in various therapeutic applications. Additionally, it may serve as a metabolite of omeprazole, providing insights into the drug's metabolic pathways and efficacy. As with many chemical substances, safety and handling precautions are essential, given its potential biological activity. Overall, Omeprazol-N-Oxide represents an important compound in the context of gastrointestinal pharmacology and drug metabolism.

Formula: C₁₇H₁₉N₃O₄S

InChI: InChI=1/C17H19N3O4S/c1-10-8-20(21)15(11(2)16(10)24-4)9-25(22)17-18-13-6-5-12(23-3)7-14(13)19-17/h5-8H,9H2,1-4H3,(H,18,19)

SMILES: Cc1cn(=O)c(CS(=O)c2nc3ccc(cc3[nH]2)OC)c(C)c1OC

Synonyms:

• 6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-1-oxido-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
• Omeprazole N-Oxide
• 6-methoxy-2-[(4-methoxy-3,5-dimethyl-1-oxido-pyridin-1-ium-2-yl)methylsulfinyl]-1H-benzimidazole
• 4-methoxy-2-(((5-methoxy-1H-benzimidazole-2-yl)sulphinyl)methyl)-3,5-dimethylpyridine 1-oxide
• 5-Methoxy-2-[((4-Methoxy-3,5-Dimethyl-1-Oxido-2-Pyridinyl)Methyl)Sulfinyl]-Benzimidazole
• 4-methoxy-2-[[(RS)-(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-3,5-dimethylpyridine 1-oxide

Omeprazole Related Compound E (4-Methoxy-2-[[(RS)-(5-methoxy-1H-benzimidazol-2-yl)sulfinyl]methyl]-3,5-dimethylpyridine 1-oxide)

CAS: 176219-04-8

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₇H₁₉N₃O₄S

Color and Shape: Off-White Powder

Molecular weight: 361.10963

Ref: 45-1478527

1H-Benzimidazole, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-1-oxido-2-pyridinyl)methyl]sulfinyl]-

CAS: 176219-04-8

Formula: C₁₇H₁₉N₃O₄S

Purity: 99%

Color and Shape: Solid

Molecular weight: 361.4155

Ref: IN-DA0024I9

Omeprazole EP Impurity E (Omeprazole N-Oxide)

CAS: 176219-04-8

Formula: C₁₇H₁₉N₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 361.42

Ref: 4Z-O-0212

4-Methoxy-2-(((5-methoxy-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,5-dimethylpyridine 1-oxide

CAS: 176219-04-8

4-Methoxy-2-(((5-methoxy-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,5-dimethylpyridine 1-oxide

Purity: 99%

Molecular weight: 361.42g/mol

Ref: 54-OR1074834

4-Methoxy-2-[[(RS)-(5-methoxy-1H-benzimidazol-2-yl)sulphinyl]methyl]-3,5-dimethylpyridine 1-Oxide (Omeprazole N-Oxide)

Controlled Product

CAS: 176219-04-8

Formula: C₁₇H₁₉N₃O₄S

Color and Shape: Neat

Molecular weight: 361.42

Ref: 86-MM0095.07

Omeprazole N-Oxide

CAS: 176219-04-8

Impurity Esomeprazole EP Impurity E/ Omeprazole Impurity E
Applications A metabolite of Omeprazole.
References Miner, P., et al.: Am. J. Gastroenterology, 98, 2616 (2003),

Formula: C₁₇H₁₉N₃O₄S

Color and Shape: White To Off-White

Molecular weight: 361.42

Ref: TR-O635015

Omeprazole EP Impurity E

CAS: 176219-04-8

Formula: C₁₇H₁₉N₃O₄S

Molecular weight: 361.42

Ref: ST-EA-CP-O9005

Esomeprazole EP Impurity E

CAS: 176219-04-8

Formula: C₁₇H₁₉N₃O₄S

Molecular weight: 361.42

Ref: ST-EA-CP-E14005

4-Methoxy-2-(((5-methoxy-1H-benzo[d]imidazol-2-yl)sulfinyl)methyl)-3,5-dimethylpyridine 1-oxide

CAS: 176219-04-8

Purity: 95.0%

Molecular weight: 361.4200134277344

Ref: 10-F234476

5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide

CAS: 176219-04-8

5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole N-oxide is an ammonium salt of a sulfoxide with a chloride. It is also known as esomeprazole magnesium. This drug is used in the preparation of pharmaceutical preparations and is used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and other conditions. The magnesium salt form is a polymorphic substance that has a crystalline form that occurs in nature, called alpha form, and a synthetic form that occurs in laboratory experiments and has been designated beta form. The alpha form exhibits enantioselectivity when it binds to the enzyme pepsin, which causes the drug to have an antiulcer effect.

Formula: C₁₇H₁₉N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 361.42 g/mol

Ref: 3D-IM57921

Omeprazole N-oxide

CAS: 176219-04-8

Omeprazole N-oxide, a metabolite of the gastric proton pump inhibitor omeprazole, serves as a potential impurity in commercial omeprazole preparations.

Formula: C₁₇H₁₉N₃O₄S

Color and Shape: Solid

Molecular weight: 361.42

Ref: TM-T84934