CAS 17630-76-1

5-Chloroisatin

Description:

5-Chloroisatin is an organic compound characterized by its structure, which includes a chloro substituent at the 5-position of the isatin framework. Isatin itself is a diketopiperazine derivative, and the presence of the chlorine atom introduces unique reactivity and properties. This compound typically appears as a solid and is known for its pale yellow to light brown color. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide but has limited solubility in water. 5-Chloroisatin is of interest in various fields, including medicinal chemistry, due to its potential biological activities, including antimicrobial and anticancer properties. The compound can participate in various chemical reactions, such as nucleophilic substitutions and cycloadditions, making it a versatile intermediate in organic synthesis. Safety data indicates that, like many halogenated compounds, it should be handled with care, as it may pose health risks upon exposure. Overall, 5-Chloroisatin serves as a valuable compound in research and development within the chemical and pharmaceutical industries.

Formula: C₈H₄ClNO₂

InChI: InChI=1/C8H4ClNO2/c9-4-1-2-6-5(3-4)7(11)8(12)10-6/h1-3H,(H,10,11,12)

InChI key: InChIKey=XHDJYQWGFIBCEP-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC1=O)=CC=C(Cl)C2

Synonyms:

• 1H-Indole-2,3-dione, 5-chloro-
• 5-Chlor-2,3-Dioxoindolin
• 5-Chlor-2,3-Indolindion
• 5-Chlorisatide
• 5-Chloro-1H-Indole-2,3-Dione
• 5-Chloro-2,3-Indolinedione
• 5-Chloro-2,3-indoledione
• 5-Chloroindole-2,3-Dione
• Akos Bbs-00000996
• Indole-2,3-dione, 5-chloro-
• Isatin, 5-chloro-
• NSC 135811
• Timtec-Bb Sbb003741
• 5-Chloroisatin
• BUTTPARK 50\07-91
• AURORA KA-5424
• 5-choroisatin
• 5-CHLOROISATIN/5-CHLORO-2,3-INDOLINEDIONE
• 5-Chlorisatin
• 5-Chloroisatin ,98%

5-Chloroisatin, 98%

CAS: 17630-76-1

5-Chloroisatin is a reagent used in the synthesis of Schiff bases through the reaction with 2-methyl-4-nitroaniline or 4-amino-4,5-dihydro-1H-1,2,3-triazole-5-one. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label inf

Formula: C₈H₄ClNO₂

Purity: 98%

Color and Shape: Orange to brown, Powder

Molecular weight: 181.58

Ref: 02-A13125

1H-Indole-2,3-dione, 5-chloro-

CAS: 17630-76-1

Formula: C₈H₄ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 181.5759

Ref: IN-DA0024L6

5-Chloroisatin

CAS: 17630-76-1

Formula: C₈H₄ClNO₂

Molecular weight: 181.58

Ref: 7W-GK3423

5-Chloroisatin

CAS: 17630-76-1

5-Chloroisatin

Formula: C₈H₄ClNO₂

Purity: 98%

Color and Shape: orange powder

Molecular weight: 181.58g/mol

Ref: 54-OR18353

5-Chloroisatin

CAS: 17630-76-1

5-Chloroisatin is a natural compound that is structurally similar to the potent anticancer agent 5-fluorouracil. 5-Chloroisatin has been shown to inhibit the growth of human breast cancer cells (MDA-MB-231) in vitro and in vivo. 5-chloroisatin forms stable complexes with malonic acid and hydrochloric acid, which are necessary for the reaction mechanism. The chemical structures of 5-chloroisatin, its reaction mechanism, and inhibition properties have been elucidated using FTIR spectroscopy, electrochemical impedance spectroscopy, and cell culture experiments. This compound also inhibits epidermal growth factor receptor (EGFR) signaling pathways by binding to EGFR inhibitor molecules that are expressed on the surface of cancer cells.

Formula: C₈H₄ClNO₂

Color and Shape: Powder

Molecular weight: 181.58 g/mol

Ref: 3D-FC52486

5-Chloroisatin

CAS: 17630-76-1

Formula: C₈H₄ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 181.58

Ref: 10-F001745