CAS 1764-85-8

Epitizide

Description:

Epitizide, with the CAS number 1764-85-8, is a chemical compound classified as a thiazide diuretic. It is primarily used in the treatment of hypertension and edema associated with various medical conditions. Epitizide functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased excretion of sodium and water, which helps to lower blood pressure and reduce fluid retention. The compound is characterized by its sulfonamide structure, which is common among thiazide diuretics, and it typically exhibits a moderate solubility in water. Epitizide may also have potential side effects, including electrolyte imbalances, dehydration, and allergic reactions, which necessitate careful monitoring during treatment. As with other medications, its use should be guided by a healthcare professional, considering individual patient factors and potential drug interactions. Overall, Epitizide is an important therapeutic agent in managing cardiovascular and renal conditions.

Formula: C₁₀H₁₁ClF₃N₃O₄S₃

InChI: InChI=1S/C10H11ClF3N3O4S3/c11-5-1-6-8(2-7(5)23(15,18)19)24(20,21)17-9(16-6)3-22-4-10(12,13)14/h1-2,9,16-17H,3-4H2,(H2,15,18,19)

InChI key: InChIKey=RINBGYCKMGDWPY-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(NC(CSCC(F)(F)F)N1)=CC(Cl)=C(S(N)(=O)=O)C2

Synonyms:

• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[[(2,2,2-trifluoroethyl)thio]methyl]-, 1,1-dioxide
• 3-[(2,2,2-Trifluoroethylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-Chloro-3,4-dihydro-3-[(2,2,2-trifluoroethyl)thiomethyl]-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-Chloro-3,4-dihydro-7-sulfamoyl-3-(2,2,2-trifluoroethylthiomethyl)-2H-1,2,4-benzothiadiazine 1,1-dioxide
• 6-chloro-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• Epitizid
• Epitizide
• Flurese
• NSC 108164
• P-2105
• Thiaver

Epitizide

Controlled Product

CAS: 1764-85-8

Applications Epitizide is a diuretic agent.
References Pilsbury, V., et al.: J. Pharm. Pharmacol., 18, 713 (1966), Tisdall, P., et al.: Clin. Chem., 26, 702 (1980),

Formula: C₁₀H₁₁ClF₃N₃O₄S₃

Color and Shape: White To Off-White

Molecular weight: 425.86

Ref: TR-E588825

Epitizide

CAS: 1764-85-8

Epitizide is a cardiac glycoside that has been found in human urine samples. The compound can be chromatographed and analyzed by spectrometric techniques. It is also possible to measure the compound using high-performance liquid chromatography with ultraviolet detection. Epitizide can be detected in cardiac glycosides, which are used for analytical toxicology and as a control in assays of other compounds.

Formula: C₁₀H₁₁ClF₃N₃O₄S₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 425.86 g/mol

Ref: 3D-FE22746

Epitizide-15N2, d2

Controlled Product

CAS: 1764-85-8

Formula: C₁₀H₉D₂ClF₃NN₂O₄S₃

Color and Shape: Neat

Molecular weight: 429.85

Ref: TR-E588827

Epitizide

CAS: 1764-85-8

Epitizide, a benzothiadiazine, commonly found in combination Triamterene , is used to produce diuresis [1] .

Formula: C₁₀H₁₁ClF₃N₃O₄S₃

Color and Shape: Solid

Molecular weight: 425.86

Ref: TM-T73218