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CAS 176486-63-8

:

(2S,4R)-FMOC-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID

Description:
(2S,4R)-FMOC-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID is a chiral amino acid derivative commonly used in peptide synthesis and medicinal chemistry. This compound features a pyrrolidine ring, which contributes to its cyclic structure and stereochemistry, specifically with the (2S,4R) configuration indicating the spatial arrangement of its substituents. The presence of the FMOC (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection during peptide synthesis, while the BOC (tert-butyloxycarbonyl) group serves a similar purpose, providing stability and protection to the amino group. The carboxylic acid functionality is crucial for its role in forming peptide bonds. This compound is typically utilized in the synthesis of peptides and other bioactive molecules due to its ability to facilitate the introduction of amino acids into growing peptide chains. Its unique structural features and protective groups make it a valuable intermediate in organic synthesis and pharmaceutical development. As with many chiral compounds, it is important to handle it with care, considering its potential biological activity and the implications of stereochemistry in drug design.
Formula:C25H28N2O6
InChI:InChI=1/C25H28N2O6/c1-25(2,3)33-24(31)27-13-15(12-21(27)22(28)29)26-23(30)32-14-20-18-10-6-4-8-16(18)17-9-5-7-11-19(17)20/h4-11,15,20-21H,12-14H2,1-3H3,(H,26,30)(H,28,29)/t15-,21+/m1/s1
Synonyms:
  • Rarechem Em Wb 0068
  • N-Boc-Trans-4-N-Fmoc-Amino-L-Proline
  • Fmoc(2S,4R)-Abpc
  • Fmoc-(2S,4R)-4-Amino-1-Boc-Pyrrolidine-2-Carboxylic Acid
  • Fmoc-Abpc(2S,4R)-Oh
  • Boc-L-Pro(4-Nhfmoc)-Oh
  • (2S,4R)-N-(Tert-Butoxycarbonyl)-4-N-(9-Fluorenylmethoxycarbonyl)Aminopyrrolidine-2-Carboxylic Acid
  • (2R,4R)-4-(((9H-fluoren-9-yl)methoxy)carbonylamino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
  • (4R)-1-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-proline
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