CAS 17650-98-5
:Ceruletide
Description:
Ceruletide, with the CAS number 17650-98-5, is a synthetic peptide that mimics the action of cholecystokinin (CCK), a hormone involved in digestion and appetite regulation. It is composed of a sequence of amino acids that facilitates its biological activity, primarily stimulating the secretion of digestive enzymes from the pancreas and promoting gallbladder contraction. Ceruletide is often used in research settings to study gastrointestinal physiology and the effects of CCK on various biological processes. The substance is typically administered via injection due to its peptide nature, which limits its effectiveness when taken orally. In terms of safety, ceruletide is generally considered to have a low toxicity profile, but its use should be monitored in clinical settings to avoid potential side effects, such as gastrointestinal discomfort. Overall, ceruletide serves as a valuable tool in both clinical and experimental research related to digestive health and metabolic regulation.
Formula:C58H73N13O21S2
InChI:InChI=1/C58H73N13O21S2/c1-29(72)49(71-57(87)40(23-31-12-14-33(15-13-31)92-94(89,90)91)68-56(86)43(26-48(78)79)69-52(82)37(16-18-44(59)73)65-51(81)36-17-19-45(74)63-36)58(88)62-28-46(75)64-41(24-32-27-61-35-11-7-6-10-34(32)35)54(84)66-38(20-21-93-2)53(83)70-42(25-47(76)77)55(85)67-39(50(60)80)22-30-8-4-3-5-9-30/h3-15,27,29,36-43,49,61,72H,16-26,28H2,1-2H3,(H2,59,73)(H2,60,80)(H,62,88)(H,63,74)(H,64,75)(H,65,81)(H,66,84)(H,67,85)(H,68,86)(H,69,82)(H,70,83)(H,71,87)(H,76,77)(H,78,79)(H,89,90,91)/t29-,36+,37+,38+,39+,40+,41+,42+,43+,49+/m1/s1
InChI key:YRALAIOMGQZKOW-HYAOXDFASA-N
SMILES:C[C@H]([C@@H](C(=O)NCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N)NC(=O)[C@H](CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]5CCC(=O)N5)O
Synonyms:- Ceruletide [USAN:INN:BAN]
- Caerulein
- 5-Oxo-L-prolyl-L-glutaminyl-L-alpha-aspartyl-O-sulfo-L-tyrosyl-L-threonylglycyl-L-tryptophyl-L-methionyl-L-alpha-aspartyl-L-phenylalaninamide
- 5-Oxo-L-prolyl-L-glutaminyl-L-aspartyl-L-tyrosyl-L-threonylglycyl-L-tryptophyl-L-methionyl-L-aspartylphenyl-L-alaninamide 4-(hydrogen sulfate) (ester)
- Ccris 3063
- Ceruletida
- Ceruletida [INN-Spanish]
- Ceruletidum
- Ceruletidum [INN-Latin]
- Unii-888Y08971B
- O-sulfo-L-tyrosyl-L-threonylglycyl-L-tryptophyl-D-norleucyl-L-alpha-aspartyl-L-phenylalaninamide
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Caerulein, Sulfated
CAS:For cellular and molecular biology applicationsFormula:C58H73N13O21S2Color and Shape:Powder, WhiteMolecular weight:1352.4Caerulein
CAS:This sulfated peptide isolated first from the skin of the Australian frog Litoria caerulea is a more potent secretagogue than its analog CCK-8. Ceruletide is applied in the diagnosis of pancreatic function and, in high dosage, for the induction of pancreatitis in experimental animals.Formula:C58H73N13O21S2Purity:97.04%Color and Shape:WhiteMolecular weight:1352.42Ceruletide
CAS:Ceruletide is a decapeptide that is a safe and effective cholecystokinin and cholecystokinin receptor agonist.Cost-effective and quality-assured.Formula:C58H73N13O21S2Purity:96.04% - 98.76%Color and Shape:White SolidMolecular weight:1352.4Caerulein, Ceruletide, Cerulein
CAS:Formula:C58H73N13O21S2Purity:(HPLC) ≥ 95.0%Color and Shape:White powderMolecular weight:1352.40Caerulein (>85%)
CAS:Controlled ProductApplications Caerulein is a ten amino acid oligopeptide that stimulates smooth muscle and increases digestive secretions. It is similar in action and composition to cholecystokinin. It stimulates gastric, biliary, and pancreatic secretion; and certain smooth muscle. It is used in paralytic ileus and as diagnostic aid in pancreatic malfunction. It is used to induce pancreatitis in experimental animal models.
References Anastasi,E., et al.: Ep., 23, 699 (1997); De Caro, G., et al.: Br. J. Pharmac Chemother., 33, 48 (1968)Formula:C58H73N13O21S2Purity:>85%Color and Shape:NeatMolecular weight:1352.4Caerulein triammonium
CAS:Caerulein is a hormone that has been shown to have cardiotoxic effects. It is a potent agent that stimulates the release of pancreatic enzymes and causes an increase in the concentration of glucose in blood plasma. Caerulein ammonium salt is used as a pharmacological agent for the treatment of acute pancreatitis and other inflammatory diseases, such as myocardial infarct and infectious diseases. The compound has also been shown to be effective in experimental models of infectious diseases, such as acute pancreatitis.Formula:C58H73N13O21S2•(H3N)3Purity:Min. 95%Color and Shape:PowderMolecular weight:1,403.5 g/mol
