CAS 17660-02-5

Scopolamine -D-Glucuronide

Description:

Scopolamine-D-glucuronide is a chemical compound derived from scopolamine, a tropane alkaloid known for its anticholinergic properties. This substance is characterized by the conjugation of scopolamine with glucuronic acid, which enhances its solubility and alters its pharmacokinetic profile. Scopolamine itself is primarily used in medicine for its ability to prevent nausea and motion sickness, as well as to induce sedation. The glucuronidation process typically occurs in the liver and is a common metabolic pathway for many drugs, facilitating their excretion. Scopolamine-D-glucuronide may exhibit reduced biological activity compared to its parent compound due to this modification. Its presence in biological systems can be indicative of scopolamine metabolism and may be relevant in pharmacological studies or toxicology. The compound is typically analyzed using techniques such as liquid chromatography-mass spectrometry (LC-MS) for its detection and quantification in various biological matrices. Overall, scopolamine-D-glucuronide serves as an important metabolite in understanding the pharmacodynamics and pharmacokinetics of scopolamine.

Formula: C₂₃H₂₉NO₁₀

InChI: InChI=1/C23H29NO10/c1-24-13-7-11(8-14(24)19-18(13)33-19)32-22(30)12(10-5-3-2-4-6-10)9-31-23-17(27)15(25)16(26)20(34-23)21(28)29/h2-6,11-20,23,25-27H,7-9H2,1H3,(H,28,29)/t11?,12-,13?,14?,15-,16-,17-,18?,19?,20?,23+/m1/s1

Synonyms:

• (-)-Scopolamine 9'-glucuronide
• (2S)-3-[[(1a,2,4,5a,7)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl]oxy]-3-oxo-2-phenylpropyl -D-Glucopyranosiduronic Acid
• Scopolamine O--D-glucuronide

Scopolamine Glucuronide

CAS: 17660-02-5

Formula: C₂₃H₂₉NO₁₀

Molecular weight: 479.48

Ref: 4Z-S-016

Scopolamine O-b-D-glucuronide

CAS: 17660-02-5

Ref: 7W-GC1628

Scopolamine β-D-Glucuronide

Controlled Product

CAS: 17660-02-5

Stability Hygroscopic
Applications A metabolite of Scopolamine.
References Shutt, L., et al.: Anaesthesia, 34, 476 (1979), Wada, S., et al.: Xenobiotica, 21, 1289 (1991), Chen, X., et al.: Acta Pharm. Sin., 33, 849(1998),

Formula: C₂₃H₂₉NO₁₀

Purity: >85%

Color and Shape: Neat

Molecular weight: 479.48

Ref: TR-S200010

Scopolamine O-b-D-glucuronide

CAS: 17660-02-5

Scopolamine O-b-D-glucuronide is a methylated derivative of scopolamine. It is an oligosaccharide that is synthesized through glycosylation and has a high purity. Scopolamine O-b-D-glucuronide is used in the synthesis of complex carbohydrates.

Formula: C₂₃H₂₉NO₁₀

Purity: Min. 95%

Molecular weight: 479.48 g/mol

Ref: 3D-MS09952

Scopolamine Glucuronide

CAS: 17660-02-5

Formula: C₂₃H₂₉NO₁₀

Molecular weight: 479.49

Ref: ST-EA-CP-S114006