CAS 176714-12-8

Glycinamide, N-[(1-mercaptocyclohexyl)acetyl]-O-methyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-(2S)-2,4-diaminobutanoyl-L-cysteinyl-L-prolyl-L-arginyl-, cyclic (1→5)-disulfide (9CI)

Description:

Glycinamide, N-[(1-mercaptocyclohexyl)acetyl]-O-methyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-(2S)-2,4-diaminobutanoyl-L-cysteinyl-L-prolyl-L-arginyl-, cyclic (1→5)-disulfide is a complex peptide compound characterized by its cyclic disulfide structure, which contributes to its stability and biological activity. The presence of multiple amino acid residues, including L-tyrosine, L-phenylalanine, L-glutamine, and L-cysteine, suggests that it may play a role in various biochemical processes, potentially including signaling pathways or enzyme activity modulation. The mercaptocyclohexyl group indicates a thiol functionality, which can participate in redox reactions and may influence the compound's reactivity and interaction with biological targets. This compound is likely to exhibit specific solubility characteristics, depending on its overall polarity and the presence of functional groups. Its complex structure may also suggest potential applications in pharmaceuticals or biochemistry, particularly in the development of peptide-based therapeutics. However, detailed studies would be necessary to fully elucidate its properties and potential uses.

Formula: C₅₂H₇₆N₁₄O₁₁S₂

Synonyms:

• Glycinamide, N-[(1-mercaptocyclohexyl)acetyl]-O-methyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-(2S)-2,4-diaminobutanoyl-L-cysteinyl-L-prolyl-L-arginyl-, cyclic (1→5)-disulfide (9CI)
• Glycinamide, N-[(1-mercaptocyclohexyl)acetyl]-O-methyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-(2S)-2,4-diaminobutanoyl-L-cysteinyl-L-prolyl-L-arginyl-, cyclic (1→5)-disulfide
• d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin

(d(CH₂)₅¹,Tyr(Me)²,Dab⁵,Arg⁸)-Vasopressin

CAS: 176714-12-8

The isosteric substitution of Asn5 by Dab in oxytocin, vasopressin and their analogs invariably leads to a dramatic loss of the biolical activities of the peptides. In OT or VP antagonists, the exchange generates highly selective and potent OT and V1a receptor antagonists.

Formula: C₅₂H₇₆N₁₄O₁₁S₂

Color and Shape: White

Molecular weight: 1137.38

Ref: 01-4145234

(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin

CAS: 176714-12-8

(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1].

Formula: C₅₂H₇₆N₁₄O₁₁S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1137.38

Ref: TM-T80137